UMELISA Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase...
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![Page 1: UMELISA Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas.](https://reader034.fdocuments.in/reader034/viewer/2022051316/56649ea85503460f94bac871/html5/thumbnails/1.jpg)
![Page 2: UMELISA Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas.](https://reader034.fdocuments.in/reader034/viewer/2022051316/56649ea85503460f94bac871/html5/thumbnails/2.jpg)
![Page 3: UMELISA Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas.](https://reader034.fdocuments.in/reader034/viewer/2022051316/56649ea85503460f94bac871/html5/thumbnails/3.jpg)
UMELISA
Birth defectsDown syndromeCongenital hypothyroidismPhenylketonuriaBiotinidase deficiencyHIV 1+2Hepatitis BHepatitis CHTLV I +IIChagas diseaseDengueLeprosyTetanusToxoplasmosisAllergy
![Page 4: UMELISA Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas.](https://reader034.fdocuments.in/reader034/viewer/2022051316/56649ea85503460f94bac871/html5/thumbnails/4.jpg)
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![Page 6: UMELISA Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas.](https://reader034.fdocuments.in/reader034/viewer/2022051316/56649ea85503460f94bac871/html5/thumbnails/6.jpg)
NATIONAL SCREENING AND NATIONAL SCREENING AND OTHER SPECIAL PROGRAMS IN OTHER SPECIAL PROGRAMS IN
CUBACUBA
•Mother - ChildMother - Child
•Blood CertificationBlood Certification
•Epidemiological SurveillanceEpidemiological Surveillance
•Placenta CertificationPlacenta Certification
•Minimum access neurosurgeryMinimum access neurosurgery
![Page 7: UMELISA Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas.](https://reader034.fdocuments.in/reader034/viewer/2022051316/56649ea85503460f94bac871/html5/thumbnails/7.jpg)
Severe Birth Defects
HIV
Hepatitis B
Hepatitis C
Congenital Hypothyroidism
Phenilketonuria
Biotinidase Def. (2002)
Galactosemia (2002)
Congenital Adrenal H. (2003)
Others
![Page 8: UMELISA Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas.](https://reader034.fdocuments.in/reader034/viewer/2022051316/56649ea85503460f94bac871/html5/thumbnails/8.jpg)
CUBAN CUBAN PRENATAL PROGRAMSPRENATAL PROGRAMS
RESULTS.RESULTS.
Pregnants Screened:Pregnants Screened: 2 524 1632 524 163
Birth Defects Detected:Birth Defects Detected: 5 2665 266
Cuba 1986 – 2001Cuba 1986 – 2001
Only 1 mother to child HIV transmission since 1997Only 1 mother to child HIV transmission since 1997
No mother to child HBV transmission in 95%No mother to child HBV transmission in 95%
2.08 x 10002.08 x 1000
![Page 9: UMELISA Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas.](https://reader034.fdocuments.in/reader034/viewer/2022051316/56649ea85503460f94bac871/html5/thumbnails/9.jpg)
CONGENITAL HYPOTHYROIDISMCONGENITAL HYPOTHYROIDISMCUBAN SCREENING PROGRAM.CUBAN SCREENING PROGRAM.
• Newborns Screened:Newborns Screened: 2 108 2882 108 288
• Hypothyroidism:Hypothyroidism: 641641• Permanent:Permanent: 325 325• Transitory:Transitory: 203 203 • Under study:Under study: 113 113
Incidence:Incidence: 1 : 32951 : 3295
Cuba 1986 – 9 -Cuba 1986 – 9 -20012001
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BLOOD CERTIFICATION ANDBLOOD CERTIFICATION ANDSEROLOGICAL SURVEILLANCESEROLOGICAL SURVEILLANCE
HIV1+2, HBsAg, HCV, DENGUE, CHAGASHIV1+2, HBsAg, HCV, DENGUE, CHAGAS
17,824,040UMELISA
13,568,060
7,314,844
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++- - +-
Negativeno further action
Negativeno further action
1 2
BL OO D
DIS CA RD
- -- - ++ +++-- -
++- - +-Negative
no further action
++- - +-Negative
no further actionFollow Up6 m onths
A B WHO
HIV SCREENING ALGORITHM
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VIH 1 and VIH 2 cases detectedVIH 1 and VIH 2 cases detectedMore than 20 million testedMore than 20 million tested
0
100
200
300
400
500
600
700
1986 1988 1990 1992 1994 1996 1998 2000
VIH 1
VIH 2
Year
Ser
opos
itiv
es
DAVIH SUMA
DETECTED4072
LIVING WITHHIV/AIDS
3022