Definition of Chemotherapeutic Drug Administration

Administration of Chemotherapeutic Agents Dosage of chemotherapeutic administration Equipment of chemotherapeutic drug

administration Implementation of administration

chemotherapeutic drugs.

Administration of chemotherapeutic drugs requires skills in additional to those used when giving other drugs .

For example some drugs require special equipment or must be given through unusual route.

Others drugs need protection from the light

specially trained nurses and physicians should give chemotherapeutic drugs.

Chemotherapeutic agents may be administered in the hospital, clinic, or home setting by topical, oral, intravenous, intramuscular, subcutaneous, arterial, intracavitary.

The administration route usually depends on the type of agent, the required dose, and the type, location, and extent of tumor being treated.

Dosage of antineoplastic agents is based primarily on the› patient’s total body surface area› previous response to chemotherapy or

radiation therapy› major organ function.

Nausea and vomiting Intestinal irritation Stomatitis Hearing loss Anemia Alopecia

Diarhea constipation Inflammation, ulceration, necrosis and

loss of vein patency.

1-Prescribed drug 2-Gloves 3-Aluminum foil 4-Normal saline solution 5-Syringe and needles 6-Normal pump or controller

Assess the patient's physical condition, and review his medical history

Make sure you understand what chemotherapeutic agent needs to be given and by what route, and provide the necessary teaching and support to the patient and his family

Confirm the patient's identity according to your facility policy

Determine the best site to administer the drug, When selecting the site, consider drug compatibilities, frequency of administration

Evaluate your patient's condition, the result of

recent laboratory studies . Determine whether the patient has received chemotherapy before ,and note the severity

of any adverse effects. Check his drug history for medications that

may interfere with chemotherapy. Talk with the physician or pharmacist before you give it.

Check the patient's chart for complete chemotherapy protocol order, including the patient's name and dosage, and route ,rate

and frequency of administration

Check to see whether the physician has ordered an antiemetic, fluids , a diuretic, or electrolyte supplements to be given before , during , or after chemotherapy administration.

Evaluate the patient's and his family's understanding of chemotherapy, and make sure the patient or a responsible family member has signed the consent form.

Put on gloves. Keep them on through all stages of handling the drug including preparation, I.V. tubing, and administration.

Before administering the drug avoid giving chemotherapeutic drugs through an existing I.V. line.

To identify an administration site, examine the patient's veins starting with his hands and proceeding to his forearm.

When an appropriate line is in place, infuse 10 to 20 ml of normal saline solution to test vein patency .

Never test vein patency with a chemotherapeutic drug. Next, administer the drug as appropriate.

Closely monitor the patient for signs of hypersensitivity reaction.

After infusion of the medication, infuse 20 ml of normal saline solution. Do this between administrations of different chemotherapeutic drugs and before discontinuing the I.V. line.

Dispose of used equipment in properly container.

Wash your hands thoroughly with soap and warm water after giving any chemotherapeutic drug

Location & description of the I.V site before treatment

Record the drug & dosage administration Sequence of drug administration Needle type and the size used Amount & type of flushing solution

Document any adverse reaction Patient’s tolerance of treatment. Topics discussed with the patient and

his family.