3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

More Pow(d)er For You -

Monetary advantages of

die table segments !

More Pow(d)er For You -

Monetary advantages of

die table segments !

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Die Table SegmentsDie Table Segments

NEW TECHNOLOGY

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Advantages of Die Table SegmentsAdvantages of Die Table Segments

Increased output

Reduced number of turrets and parts

Reduced change over time

Reduced cleaning time

Less product loss

Reduced ejection force

Uniform hardness of shaped tablets

Longer life time

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Increased number of stations per die table

Advantages of Die Table SegmentsIncreased outputAdvantages of Die Table SegmentsIncreased output

Up to 25 %25 % more output

OLDup to ø1636 stations EU19 max. filling depth 18mmmax. output: 248.400 tabl/h

NEW !up to ø1845 stations EU19 max. filling depth 22mmmax. output: 310.500 max. output: 310.500 tabl/htabl/h

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Increased number of stations per die table

Output increase at tablet size

0%

25%

20%

5%5%

25% 24%

14%

3%

23%

12% 12%

0%

5%

10%

15%

20%

25%

30%

13 16 25 25-441

BB B D D-441

max. tablet diameter

1090/1200

2090/2200

3090/3200

Advantages of Die Table SegmentsIncreased outputAdvantages of Die Table SegmentsIncreased output

Up to 25 %25 % more output

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

2090i - single dies 2090i - 3 die table segmentsup to ø11: 47 Stations-EU19max. Filling depth 18mmmax. Output: 324.300 Tabl/hup to ø13: 43 Stations-EU19 up to ø18: 45 Stations-EU19max. Filling depth/Fülltiefe 18mm max. Filling depth 22mmmax. Output: 296.700 Tabl/h max. Output: 310.500 Tabl/hup to ø16: 36 Stations-EU19max. Filling depth 18mmmax. Output: 248.400 Tabl/h

Only 1 segment turret instead of 3 turrets for the same production

BBS, BB, B: all 3 sizes can be run on one segment only by changing the segments

Advantages of Die Table SegmentsReduced number of partsAdvantages of Die Table SegmentsReduced number of parts

Reduced equipment costs

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

No dies and die screws necessary

Advantages of Die Table SegmentsReduced number of partsAdvantages of Die Table SegmentsReduced number of parts

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

No dies and die screws necessary

Advantages of Die Table SegmentsReduced number of partsAdvantages of Die Table SegmentsReduced number of parts

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

No dies and die screws necessary

Only 3 segments for a 2090i instead of 47 dies + 47 die screws

Advantages of Die Table SegmentsReduced number of partsAdvantages of Die Table SegmentsReduced number of parts

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Advantages of Die Table SegmentsReduced change over timeAdvantages of Die Table SegmentsReduced change over time

Complete turret with segments

One die segment removed

Compatible to standard presses

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

No dies and die screws necessary

Many die screws replaced by 6 or 10 segment screws

Many dies replaced by few segments

Only 3 or 5 segments depending on tablet press type

Advantages of Die Table SegmentsReduced change over timeAdvantages of Die Table SegmentsReduced change over time

Extremely short change over time

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Time consuming adjustment of dies to punches for special format tablets no longer required

Advantages of Die Table SegmentsReduced change over timeAdvantages of Die Table SegmentsReduced change over time

Maximised productivity

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Advantages of Die Table SegmentsReduced change over timeAdvantages of Die Table SegmentsReduced change over time

Easy segment fixing by 2 screws for every segment

Conventional with a 2090i: loosening and removing 36 screws, removing 36 dies

Now: dismantling 6 clamping wedges and 6 screws, remove 3 die table segments

Only 9 manual actions instead of the conventional 72

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Advantages of Die Table SegmentsReduced cleaning timeAdvantages of Die Table SegmentsReduced cleaning time

No screw holes and no die bores

Fewer parts

Cleaning of a few (3 or 5) segments instead of many dies and die screws

No cleaning of screw bores

No cleaning of die seats

1.Step

2. Step

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Advantages of Die Table SegmentsReduced cleaning timeAdvantages of Die Table SegmentsReduced cleaning time

Screw holes and die boresDIE BORES

SCREW HOLES

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Advantages of Die Table SegmentsReduced cleaning timeAdvantages of Die Table SegmentsReduced cleaning time

NoNo die bores and nono screw holes Very easy and fast cleaning of die table segments

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

No screw holes and no die bores

Advantages of Die Table SegmentsReduced cleaning timeAdvantages of Die Table SegmentsReduced cleaning time

Cleaning work is significantly easier

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Advantages of Die Table SegmentsLess product lossAdvantages of Die Table SegmentsLess product loss

ROUGH EDGES

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

NO ROUGH EDGES

Advantages of Die Table SegmentsLess product lossAdvantages of Die Table SegmentsLess product loss

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

in comparison toNO ROUGH EDGES ROUGH EDGES

Advantages of Die Table SegmentsLess product lossAdvantages of Die Table SegmentsLess product loss

Decrease of product loss

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Advantages of Die Table SegmentsLess product lossAdvantages of Die Table SegmentsLess product loss

No rough edges

Scraper slides over plane surface

Die table segments surfaces are smooth

No gaps between die table and dies

Product loss reduced by more than 50%

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Significant reduction in wall friction during tablet ejection due to hard segment with extremely smooth surface

Low wall friction during ejection minimizes loss of tablet hardness

Lower pressing forces are required

Longer lifetime as a result of reduced stress

Advantages of Die Table SegmentsReduced ejection forceAdvantages of Die Table SegmentsReduced ejection force

Reduced ejection force

Longer lifetime

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Cavities are parallel orien-tated to the circumference. So hardness variation due to centrifugal force difference between in- and outside is reduced to the possible minimum.

Advantages of Die Table SegmentsUniform hardness of shaped tablets Advantages of Die Table SegmentsUniform hardness of shaped tablets

Less variation in hardness of shaped tablets

Better hardness

More uniform fill

Better standard deviation

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Replacement of dies held in position by die screws by clamped segments makes it possible to increase the bore hardness

Segments – like dies – can be used on both sides to extend timelife

Robust material reduces wear

Segments made of special high-alloy steel

Advantages of Die Table SegmentsLonger LifetimeAdvantages of Die Table SegmentsLonger Lifetime

Longer lifetime

Less wear and tear

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Compatible with the PT/P and i generations

Also a huge increases in performance on presses of former generations

Available in AISI 316L for WiP presses

Compatible with the PT/P and i generationsCompatible with the PT/P and i generations

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Die Table SegmentsDie Table Segments

Increasedoutput

Additional profit & Cost saving

Reducednumberof parts

Reducedchange

over time

Reducedcleaning

time

Lessproduct

loss

Longerlifetime

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Die Table SegmentsDie Table Segments

- More Pow(d)er For You -

Monetary advantages of die table segments !

How is it possible to calculate the monetary advantages ?

- More Pow(d)er For You -

Monetary advantages of die table segments !

How is it possible to calculate the monetary advantages ?

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Monetary advantages of Die Table SegmentsMonetary advantages of Die Table Segments Increased output

2090i without with

EU 19 up to ø13 Die Table Segments

run time [h]/shift 6,75 6,75

shifts /day 2 2

number of stations 43 45

turret rotation speed [rpm] 60 60

output/hour [pieces] 154.800 162.000

output/day [pieces] 2.089.800 2.187.000

output increase [%]   4,65%

workdays/year 220 220

profit/tablet [€] 0,05 € 0,05 €

profit/h [€] 7.740 € 8.100 €

additinal profit/h [€]   360 €

additional profit/day [€]   4.860 €

additional profit/year [€]   1.069.200 €

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Reduced change over time2090i without with

EU 19 up to ø13 Die Table Segments

number of stations 43 45

# of units (dies or segments) 43 3

time to assemble oblong upper+lower punches [Min]   20

time to assemble 3 segments [Min]   5

time to assemble oblong upper+lower punches + die/station [Min]

3 1/2  

time to loosen + remove [Min] 3 1/2 25

time for change-over [Min] 301 50

labor costs/h [€] 40 € 40 €

time for change-over [h] 5,02 0,83

frequency/month 8 8

total costs of change-over/month [€] 1.605 € 267 €

savings from new to old/month [€]   1.339 €

savings from new to old/year [€]   16.064 €

Monetary advantages of Die Table SegmentsMonetary advantages of Die Table Segments

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Reduced cleaning time2090i without with

EU 19 up to ø13 Die Table Segments

number of stations 43 45

number of screws 43 6

# of units (dies or segments) 43 3

cleaning time of die table bore [Min] 1 0

cleaning time of screw hole [Min] 1 1

automatically cleaning of dies+screws resp. segments [Min]

40 10

cleaning time [Min] 126 16

labor costs/h [€] 40 € 40 €

cleaning time [h] 2,10 0,27

frequency/month 8 8

total costs of cleaning/month [€] 672 € 85 €

savings from new to old/month [€]   587 €

savings from new to old/year [€]   7.040 €

Monetary advantages of Die Table SegmentsMonetary advantages of Die Table Segments

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Reduced product loss2090i without with

EU 19 up to ø13 Die Table Segments

number of stations 43 45

product loss [%] 1,50% 1,00%

turret rotation speed [rpm] 60 60

output/hour [pieces] 154.800 162.000

output/day [pieces] 2.089.800 2.187.000

workdays/year 220 220

tablet production/year 459.756.000 481.140.000

product loss in # of tablets/year 6.896.340 4.811.400

product loss reduction in # of tablets/year   2.084.940

profit/tablet [€] 0,05 € 0,05 €

additional profit/year [€]   104.247 €

Monetary advantages of Die Table SegmentsMonetary advantages of Die Table Segments

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Longer life time2090i without with

EU 19 up to ø13 oblong Die Table Segments

number of stations 43 45

# of units (dies or segments) 43 3

single unit price (double-sided tapered dies - oblong) [€] 91,00 €  

single tapered segment with 15 stations (oblong) [€]

 1.290,67 €

set price [€] 3.913,00 € 3.872,01 €

tablet production/year [pieces] 459.756.000 481.140.000

anual compr./ station 10.692.000 10.692.000

life time per station 7.000.000 14.000.000

sets per year 1,53 0,76

set cost per year [€] 5.976,83 € 2.957,11 €

additional profit/year [€]   3.020 €

Monetary advantages of Die Table SegmentsMonetary advantages of Die Table Segments

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

increased output 1.069.200 €

reduced change over time 16.064 €

reduced cleaning time 7.040 €

reduced product loss 104.247 €

longer life time 3.020 €

TOTAL BENEFIT QUANTIFICATION /YEAR 1.199.571 €

Monetary advantages of Die Table SegmentsMonetary advantages of Die Table Segments

3RD Arab-European Pharma Seminar 2004 © All rights reserved by Fette GmbH, also in case of pending patens. All uses, e.g. like copying or disclosure to third parties, strictly restricted to us.

Die Table SegmentsDie Table Segments

It‘s your decision, if you want

the to be yours !

It‘s your decision, if you want

the to be yours !