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¼ . ü $ 5 S ï) * P...Ý + u $ ( $ c â Silica, Florisil, Alumina, Diol, NH 2, CN C 18, tC 18, C...
2
Oasis 2 x 4 ޘອහၤ ዹອᒠ ቯ። Q नሤᇢএଋऱजఎख၅ኡ Q భབྷ߹95%ڹࡨĂᒂलĂᒂಢᒠছᇕ Q ഗႥৎLjభᏴᒮᄟୈሆဧ Q ᎌၺቶLjభဏછຳݷᔫ QpHᒋपᆍ:1 - 10 Q အອ Q ᄏጘ ) ኪ / ฬ * Q ၺ Q ᅉ Q ᇕᏎቶዹອᒦ၌ጇॊᇜ Q ጇࡔኧዐ Q ኪጘᒦလ໕ᾡᏪᄲ Q ኪጘᒦࡍ߅൧Ⴄ N - ጰᇭ៥ᅱᄲ - औጰᇭ۽ᇕ Q ഔᎌቶᇕ၅ኡ Q ᄰቯLjनሤᇢএଋ Q ᎌၺቶLjభဏછຳݷᔫ Q ݙ๚ߥছ QpHᒋपᆍ:0 - 14 Q အອ Q ᄏጘ ) ኪ / ฬ * Q ၺ Q ᅉ Q છᓥອ Q ఝညႤ ) ᄿ᪕ႤĂെඕႤLjળڙਜ਼ β- ดΊڙಢఝညႤLjᇝᦖಢLj ૮ႤLjᇭLj႐ણႤLjࡍણด῝ಢLjሹ᠈᠖LjᇭΊڙ* Q แጇݮഔ ) ળΊᱱಢ߹ݻଋLjړଡႭ῝ಢแጇ * Q ᱐ਜ਼ਖ਼ᛟႭॊಭ Q ᄰညᇕࡍॊᔇᅙዎࠀಯ Q ੩ᎌ૦ᇕĂણஹᎁሌᇁᇕĂดॊබছᇕ N - ጰᇭ៥ᅱᄲ - औጰᇭ۽ᇕᒠ - SO 3 H Q ᎖ସቶછᇕᇢএ )PKa 2-10* Q ᎌᎧ HLB ሤᄴჅᎌᎁ Q ᎄးுછআᏭዹອᒠ QpHᒋपᆍ:0 - 14 Q အອ Q ᄏጘ ) ኪ / ฬ * Q ၺ Q ᅉ Q ସቶጇᇕ Q β-၊ᄏ૮ଋǗળڙLjଡድᛚᠦLjᇀᅘອ Q ཪဝൊǗஉᔃLj༼ ڙQ ᒦጇᒦᇀᄿସሢଶ އN - ጰᇭ៥ᅱᄲ - औጰᇭ۽ᇕᒠ - CH 2 N(CH 3 ) 2 C 4 H 9 Q ᎖Ⴍቶછᇕᇢএ )PKa 2-8* Q ᎌᎧ HLB ሤᄴჅᎌᎁ Q ᎄးுછআᏭዹອᒠ QpHᒋपᆍ:0 - 14 Q အອ Q ᄏጘ ) ኪ / ฬ * Q ၺ Q ᅉ Q Ⴍቶጇᇕ Q ᅉඕႤLj႐ણႤLjඕႤLj༓ඕႤLjఌگድLjᠯጰࡔቝᇕ Q Ⴁ N - ጰᇭ៥ᅱᄲ - औጰᇭ۽ᇕᒠ - COOH Q ༓ସቶછᇕᎌᄂፊቶᇢএ )PKa >10* Q ᎌᎧ HLB ሤᄴჅᎌᎁ Q ᎄးுછআᏭዹອᒠ QpHᒋपᆍ:0 - 14 Q အອ Q ᄏጘ ) ኪ / ฬ * Q ၺ Q ᅉ Q ༓ସቶጇᇕ Q ۾JPMHLW ਉऱऱजǖ၍ݩᒦඕႤ )Streptomycin* ਜ਼ၷ༶ඕႤ )dihydrostreptomycin* Q ݻڻుLjݻ N - ጰᇭ៥ᅱᄲ - औጰᇭ ۽ᇕᒠ - CH 2 - ᠃ᠼણ Q ༓Ⴍቶછᇕᎌᄂፊቶᇢএ )PKa <1* Q ᎌᎧ HLB ሤᄴჅᎌᎁ Q ᎄးுછআᏭዹອᒠ QpHᒋपᆍ:0 - 14 Q အອ Q ᄏጘ ) ኪ / ฬ * Q ၺ Q ᅉ Q ༓Ⴍቶጇᇕ Q ባᅱળႭ Q ߅Ⴄ ) ඦલLjલLjᛒݩLjᱥᒂLj᎑Lj๔ࡢᎭLjᓜಽ౸Lj ಸࠔLjቤLjೡ౸ * Oasis HLB Oasis PRiME HLB Oasis MCX Oasis MAX Oasis WCX Oasis WAX ᆼᄂৼሤ᜵ནᄘ೯ )SPE* Ⴅኡᐋఌ Oasis 2X4 ऱजኧ . း᎖ႭĂସĂᒦቶછᇕSPEऱजఎख ዹອ ቃᓏਖ ) ጲ Oasis ® ᆐ * 1-10 mL 1 cc / 30 mg ᑗ 3 cc / 60 mg 10-100 mL 3 cc / 60 mg ᑗ 6 cc / 200 mg 100-500 mL 6 cc / 200 mg ᑗ 6 cc / 500 mg 500-1000 mL 6 cc / 500 mg)LP* ᑗ 12 cc / 1 g)LP* SPE ቃᓏਖኡᐋᒎฉăLP= ࡍೃ (60 μm) ᓖǖᑣOasis uElutionᄋན—።ऱښ1Ljᇸᅙ2খᆐ5%ړၺ 60;40ጰᱲ;ଡ ።ऱښ2Ljᇸᅙ2খᆐ2%ଡႭ 60;40ጰᱲ;ଡ ዹ ᇸǖଡ:ၺ = 5:95 ᇸᅙ PRiME HLBǖጰᱲ:ଡ = 90:10 HLBǖଡ ᑬखᎧᏳ (ဧμElutionޘອᐌభဏݛᒾ) Oasis PRiME HLB/HLB ᄰऱज . ᔫᆐनሤSPEऱजఎख
Transcript of ¼ . ü $ 5 S ï) * P...Ý + u $ ( $ c â Silica, Florisil, Alumina, Diol, NH 2, CN C 18, tC 18, C...
Oasis 2 x 4
95%
pH :1 - 10
/
N - -
pH :0 - 14
/β-
N - - - SO3H
PKa 2-10HLB
pH :0 - 14
/ β-
N - - -
CH2N(CH3)2C4H9
PKa 2-8HLB
pH :0 - 14
/
N - - - COOH
PKa >10HLB
pH :0 - 14
/
JPMHLW Streptomycin dihydrostreptomycin
N - - - CH2 -
PKa <1 HLB
pH :0 - 14
/
Oasis MAX
Oasis MCX
Oasis HLB
Oasis WAX
Oasis WCX
Oasis HLB
Oasis PRiME HLB
Oasis MAX
Oasis MCX
Oasis HLB
Oasis WAX
Oasis WCX
Oasis MCX
Oasis MAX
Oasis MCX
Oasis HLB
Oasis WAX
Oasis WCX
Oasis MAX
Oasis MAX
Oasis MCX
Oasis HLB
Oasis WAX
Oasis WCXOasis WCX
Oasis MAX
Oasis MCX
Oasis HLB
Oasis WAX
Oasis WCX
Oasis WAX
SPE
Oasis 2X4 SPE
Oasis®
1-10 mL 1 cc / 30 mg 3 cc / 60 mg
10-100 mL 3 cc / 60 mg 6 cc / 200 mg
100-500 mL 6 cc / 200 mg 6 cc / 500 mg
500-1000 mL 6 cc / 500 mg LP 12 cc / 1 g LP
SPE LP= (60 µm)
Oasis uElution — 1 2 5% 60 40
2 2 2% 60 40
: = 5:95
PRiME HLB : = 90:10HLB
( µElution )
Oasis PRiME HLB/HLB SPE
Silica, Florisil, Alumina, Diol, NH2 , CN C18, tC18, C8, Diol, PoraPak, RDX, NH2 , CN Accell Plus QMA, Accell Plus CM, PSA
PH ( )
Sep-Pak® Silica SiO2
: ≤3.2%/ PAHs
Sep-Pak® Florisil MgO • SiO
: ≤2.5%/
OCP’s, PCB’s
Sep-Pak® Alumina A,B,N
( , , )Al2O3 pH
: ≤1.5%
/
& Sep-Pak® Aminopropyl -Si(CH2)3NH2
/pH 8 /
,
Sep-Pak tC18
-SiC18H37 17%
/
Sep-Pak C18
-Si(CH3)2C18H37
tC18
12% /
ganglioside
Sep-Pak C8
-Si(CH3)2C8H17
HLB C18
/
Sep-Pak Accell Plus CM
/–COO-Na
/
Sep-Pak Accell Plus QMA
/
–C(O)NH(CH2)3N(CH3)3+Cl-
/
Sep-Pak
Sep-Pak DNPHLC
:55 - 105 µm
EPA TO-11A ASTM D5197 JPMOE
Sep-Pak X PoSureTM
LC
:500 - 1000 µm
JPMHLW EPA TO-11A IP-6A ASTM D5197 NIOSH 2532
Sep-Pak AC2 JPMHLW 1,4-
Sep-Pak/Carbon/Amino/
JPMHLW JPMHLW propham
Sep-Pak Carbon/PSA/ - PSA NH2
JPMHLW
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