© 2010 Mindray Confidential BC-5300 Small & Big. A compact 5-diff solution Small size Big content.

© 2010 Mindray Confidential

BC-5300 Small & Big

A compact 5-diff solution

Small size Big content

Complete solution for hematology tests Economical running Accurate and stable performance Friendly user interface Excellent information management Easy maintenance

∑

WBC

Total No

Lymphocytes (#,%)

Monocytes (#,%)

Neutrophils (#,%)

Eosinophils (#,%)

Basophils (#,%)

DIFF WBC/BASO

RUO

Atypical Lymphocytes (#,%)

Large Immature Cell (#,%)

PLT

Total No

MPV

PCT

PDW – CV

RBC

Total No

HGB

HCT

MCV

MCH

MCHC

RDW – CV,SD

Complete CBC+5DIFF result

23+4Parameters

5 Reagents

2 YEARSHELF LIFE

Original quality control and calibratorBC-5D and SC-CAL PLUS

Participation in online QC programCBC-Monitor

QC & Calibrator

20 ul sample volumewhole blood & capillary blood

60 tests/hr throughputreport ready within 1min

Lateral needle apertureavoid sample blockage

0 daily maintenanceautomatic shutdown

Economical running

Reagent Consumption

Save every drop of reagent

Low reagent consumption per test

Low dead volume per bottle

Less maintenance

Neu%

y = 0.921x + 5.7703R2 = 0.9378

0

20

40

60

80

100

120

0 20 40 60 80 100 120

Manual differential count(%)

BC

-53

00

(%)

Lym%

y = 0.9219x + 0.8691R2 = 0.9351

0

20

40

60

80

100

0 20 40 60 80 100

Manual differential count(%)B

C-5

30

0(%

)

Mon%

y = 0.7313x + 1.2876R2 = 0.563

0

5

10

15

20

25

0 5 10 15 20 25 30


BC

-53

00

(%)

Eos%

y = 0.9167x + 0.53R2 = 0.8279

0

5

10

15

20

25

30

35

0 5 10 15 20 25 30


BC

-53

00

(%)

Bas%

y = 0.6528x + 0.6109R2 = 0.4553

0

2

4

6

8

10

12

14

16

0 5 10 15 20


BC

-53

00

(%)

Correlation with microscopic counting

WBC

y = 1.0272x - 0.0566R2 = 0.9975

0

5

10

15

20

25

30

35

40

0 10 20 30 40

LH-750

BC

53

00

Neu%

y = 0.9514x + 3.9162R2 = 0.9862

0

20

40

60

80

100

120

0 20 40 60 80 100 120

LH-750B

C5

30

0

Lym%

y = 1.011x + 0.4576R2 = 0.9904

0

10

20

30

40

50

60

70

80

90

0 20 40 60 80 100

LH-750

BC

53

00

Mon%

y = 0.8019x - 0.7909R2 = 0.8921

0

2

4

6

8

10

12

14

16

18

0 5 10 15 20 25

LH-750

BC

53

00

Eos%

y = 0.9515x + 0.3626R2 = 0.9605

0

5

10

15

20

25

30

0 5 10 15 20 25 30

LH-750

BC

53

00

RBC

y = 0.9856x + 0.0621R2 = 0.9971

0

1

2

3

4

5

6

7

8

0 2 4 6 8

LH-750

BC

53

00

Correlation with Beckman Coulter LH750

Integrate-All for Operation, Maintenance & Management

Function

Shortcut

Function

Shortcut

Patient

Information

Patient

Information

Test Results

40000

Test Results

40000

FlagsFlags

GraphicsGraphicsMenuMenu

Integrated information

SearchSearch

Workload

Statistics

Workload

Statistics

Patient

Record

Patient

Record

Trend

Screen

Trend

Screen

Easy search and delta-check capability

Special

Insert lab logo or patient photoInsert lab logo or patient photo

Patient information

Patient information

Report HeadlineReport Headline

Customize results:

- parameters- graphics- flags- microscopic

Customize results:

- parameters- graphics- flags- microscopic

Customization on report styles

Auto maintenance set-upAuto maintenance set-up

“Double-click” maintenance“Double-click” maintenance

“Single-click” error removal“Single-click” error removal

Easy and convenient maintenance

Advanced technology

Digital sheath

flow

Chemical dye

Flow cytometry

Laser scatter

DC method for basophils

WBC/BASO Bath

LH Lyse

RBC Lymphocyte Monocyte Basophil Eosinophil Neutrophil

525

nm

HGB

LH lyse shrinks the white blood cells to reduce the size except for basophils;

Digital sheath flow

Good correlation with XE-2100, which uses DC-sheath-flow to test RBC.

After Digital sheath flow

MCV

y = 1. 0813x - 6. 5636R2 = 0. 983

0

20

40

60

80

100

120

140

0 50 100 150XE- 2100

Auto

load

ing/

CBC+

Diff

MCV

y = 1. 0813x - 6. 5636R2 = 0. 983

0

20

40

60

80

100

120

140

0 50 100 150XE- 2100

Auto

load

ing/

CBC+

Diff

RDW- CV

y = 0. 8488x + 0. 5229

R2 = 0. 9534

0

5

10

15

20

25

0 10 20 30XE- 2100

Auto

load

ing/

CBC+

Diff

RDW- CV

y = 0. 8488x + 0. 5229

R2 = 0. 9534

0

5

10

15

20

25

0 10 20 30XE- 2100

Auto

load

ing/

CBC+

Diff

RDW - SD

y = 1. 1217x - 0. 2602

R2 = 0. 9504

0

20

40

60

80

100

120

0 20 40 60 80 100

XE- 2100

Autoloading/CBC+Diff

RDW - SD

y = 1. 1217x - 0. 2602

R2 = 0. 9504

0

20

40

60

80

100

120

0 20 40 60 80 100

XE- 2100

Autoloading/CBC+Diff

Scattergram and flags

DIFFDIFF BASOBASO

LymLym

MonMon NeuNeu

EosEosBosBosEOS

LYM

ALY

MON

LIC

LEFTSHIFT

DIFF

NEU

GHO

Bas

Normal sample

Male, 27 years old, volunteer, healthy

WBC DIFF (n=200)

Neutrophilic band granulocyte

1%

Neutrophil 54%

Lymphocyte 37%

Monocyte 4%

Eosinophil 3.5%

Basophil 0.5%

RBC morph Normal

PLT morph Normal

Microscopic examination results


1 Neutrophil2 Lymphocyte

Normal sample

Neutrophilia

Female, 16 years old, outpatient

Diagnosis: pyrexia (pathogeny to be confirmed)

WBC DIFF (n=200)


3%

Neutrophil 81%

Lymphocyte 10%

Monocyte 3.5%

Eosinophil 2%

Basophil 0.5%

RBC morph Normal

PLT morph Normal



1 Neutrophil

1 Neutrophil

1 Neutrophil

1 Neutrophil

Neutrophilia

WBC DIFF (n=200)

Neutrophil 42.5%

Lymphocyte 28 %

Monocyte 4.5 %

Eosinophil 24.5%

Basophil 0.5%

RBC morph Normal

PLT morph Normal

Eosinophila


Diagnosis: edema (checking for pathogenesis)



1 Neutrophil

1 Neutrophil

2 Eosinophil

2 Eosinophil

Eosinophila

Immature cell

Male, 34-year-old, outpatient

Diagnosis: adult still



WBC DIFF (n=200)

Myelocytes 1%

Metamyelocytes 2.5%


2%

Neutrophil 66.5%

Lymphocyte 22.5%

Monocyte 3.5%

Eosinophil 1.0%

Basophil 1.0%

RBC morph Normal

PLT morph Normal

1 Myelocyte

2 Lymphocyte

Immature cell

Atypical lymphocyte

Female, 2 years old, inpatient

Diagnosis: bronchopneumonia; virus infection confirmed



WBC DIFF (n=200)


1%

Neutrophil 14%

Atypical lymphocyte 5 %

Lymphocyte 75.5 %

Monocyte 3%

Eosinophil 0.5 %

Basophil 1.0%

RBC morph Normal

PLT morph Normal

1 Atypical lymphocyte

Atypical lymphocyte

Iron Deficiency Anemia (IDA)


She had a CBC routine test after receiving treatment for iron deficiency anemia.

WBC DIFF (n=200)

Neutrophil 65%

Lymphocyte 30%

Monocyte 3.0%

Eosinophil 1.5%

Basophil 0.5%

RBC morph Cells vary in size

PLT morph Normal



1 Neutrophil

Iron Deficiency Anemia (IDA)

Chronic Myelocytic Leukemia (CML)

1 Neutrophil

2 Basophil

Male, 32 years old.

Chief disease: leucocytosis for 2 years

Bone marrow examination result shows a possibility of chronic myelocytic leukemia.

WBC DIFF (n=200)

Myelocytes 1.0%

Metamyelocytes 1.0%


2.0%

Neutrophil 46%

Atypical Lymphocyte 1.0%

Lymphocyte 37%

Monocyte 8.0%

Basophil 4.0%

RBC morph Normal

PLT morph Normal



Chronic Myelocytic Leukemia (CML)

Thank you!

© 2010 Mindray Confidential BC-5300 Small & Big. A compact 5-diff solution Small size Big content.

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Transcript of © 2010 Mindray Confidential BC-5300 Small & Big. A compact 5-diff solution Small size Big content.