Working backwards product Recognize product about

Post on 04-Feb-2022

2 views 0 download

Transcript of Working backwards product Recognize product about

How to solve synthesisproblems

1 Working backwards fromthe product Recognizein the product clues about

the last reaction

study tip find a friend write

out reactions only show yourfriend the product and havethem guess the startingmaterial and reagent

Presumes you know the

roadmap

2 Count carbons in productsvs the starting material

Do you need to makeor break a C C bond

ftp.CHRXMakes

etrahaloalkanes

E O Oil it

1 SiazBH 2 Haqq Th C H R C Rnon Markovnikov

toi t f

k i se e HSS04,12504,1120

IEiEE n

3I

nopeatorso ae MEN

µSO IHR J

z I Ed E your

05u ro n e Ov esters O i

r iN nxI BHS 2 702 1100

V of Yon.Markovnikov Syn

i piiiiiiii

s 8 o Eye

f

Eof a E

3membered ring

a E np S Te t na t

e on IEEE EtT t'ts er si

fM s o

jes u

1

G carbons G carbons

yppOH vicinal didIs Wao't sandditin

Alkane

FBI 91 2 tsgateBr

TLd EzNotChina

7 carbons T carbons

eats E ETERacemic

Alkane Alcohol Syn addition ofIt and OH OH on le substituted

127b

TDBH

4753 wastHalite

I 1743

V EZ 4Notchiral

7 carbons 7 carbons

ofIII nah't

L Kiki LianeRacemic

AlkaneHalohydrin

IBI fashome want it

Not or

chiral Gt3AsrLd

C C bonds must use

broken ozonolysis11 carbons 8 carbons

e t

Alkane 30 Aldehydebroke

112 940327GHz zS

Br no

say.EE xEYsE2d

Zaitsev

3 carbons8 carbon5 carbons Br NEGI

ra t mineI23 g G S L

Zz g

b 8

Alkene Holo Hee E alkene

d EE iEIt quaBr NHzBr Racer.ie

m

isrEEogruEsnsl

s iEYgx

u Sv2

wwwH