Diabetic NephropathyDiabetic RetinopathyHypercholesterolemiaOral MucositisGoutAcute Lymphocytic LeukemiaBone MetastasisBrain CancerBreast CancerCervical CancerChronic Lymphocytic LeukemiaEndometrial CancerEwing SarcomaGastric CancerGastrointestinal Stromal TumorsHead And Neck CancerHodgkin LymphomaKidney CancerLiver CancerMalignant MesotheliomaMedullary Thyroid CancerMelanomaMultiple MyelomaNon-Hodgkin LymphomaNon-Small Cell Lung CancerOvarian CancerPancreatic CancerTesticular CancerThyroid CancerAge Related Macular DegenerationKeratoconjunctivitis sicca (Dry Eye)Retinal Vein OcclusionAcute Respiratory Distress SyndromeSepsisStaphylococcal InfectionsAcute Coronary SyndromeAngina PectorisAtrial FibrillationCoronary Artery Disease (CAD)Critical Limb IschemiaHypertensionPulmonary Arterial HypertensionAcute PainAnxiety DisordersChronic PainDementiaDiabetic NeuropathyObsessive-Compulsive DisorderOsteoarthritis PainParkinson's DiseasePost-Traumatic Stress DisorderRestless Legs SyndromeSchizophreniaTraumatic Brain InjuryLiver CirrhosisChildhood EnuresisGrowth Hormone DisordersHyperparathyroidismHyperthyroidismGuillain-Barre SyndromeCytomegalovirusFungal InfectionsGram-Negative Bacterial InfectionsH1N1 InfectionHerpes ZosterHIV-1 InfectionHuman Papillomavirus InfectionsStaphylococcus Aureus (MRSA)

Cardiovascular Devices Prosthetic Heart Valve

Peripheral Vascular Devices Cardiovascular Monitoring & Diagnostic Devices

Cardiovascular Surgery Cardiac Rhythm Management

Cardiovascular Prosthetic Devices Interventional Cardiology

Cardiac Assist Devices Wound Care Management

Hospital Supplies Syringes and Needles

Disposable Hospital & Surgical Supplies Drug Delivery Devices

Inhalation Systems Needle Free Injections

Infusion Systems Diabetes Care Devices

Insulin Delivery & Glucose Monitoring Ophthalmic Devices

Cataract Surgery Devices Ophthalmic Diagnostic Equipment

Refractive Surgery Devices ENT Devices

Hearing Implants Diagnostic Devices

Electrosurgical Devices Dental Equipment & Accessories

Diagnostic Imaging & MRI Systems C/T Systems & Mammography Equipment

X-Ray & Ultrasound Systems Nuclear Imaging Equipment

Contrast Media InjectorsBone Densitometry

Anesthesia and Respiratory Devices Anesthesia Machines & Disposables

Respiratory Devices & DisposablesSleep Apnea Diagnostic Systems

Healthcare IT Medical Imaging Information Systems

Nephrology and Urology Devices Renal Dialysis Equipment

Orthopedic Devices Orthobiologics & Arthroscopy

Joint Reconstruction Trauma Fixation

Orthopedic Prosthetics Cranium Maxillofacial Fixation (CMF)

Spinal Surgery Endoscopy Devices & instruments

Rigid & Flexible Endoscope In Vitro Diagnostics

Genetic Testing Clinical Chemistry

Hematology Immuno Chemistry

Infectious Immunology Histology And Cytology

Patient Monitoring Multiparameter Patient Monitoring Micro-Electromechanical Systems

Non-invasive Blood Pressure Monitors Neurology Devices

Neurostimulation Devices Interventional Neurology

CSF Management Neurosurgical Products

Radiosurgery

ME

DT

EC

H

&

DI

AG

NO

ST

IC

S

BI

OP

HA

RM

AC

EU

TI

CA

LS

Value to the

Lead Investor

Healthcare’s Investment Marketplace

Dis

cove

ry

Dev

elop

-

men

t IND P

has

e I

Ph

ase

II

Ph

ase

III

NDA A

pp

rova

l

Lau

nch

Gro

wth

Mat

ure

Healthcare Development & Financing Cycle

IPO / Public MarketsVenture CapitalAngels / Founders Private Equity / M&A

SEE

D

EX

IT

… E M E R G I N G G R O W T H C O M PA N I E S

… ‘ L E A D ’ I N V E S T O R S

… D I R E C T I N V E S T O R S

… S T R AT E G I C PA R T N E R S & B U Y E R S

T R A N S F O R M I N G H E A LT H C A R E C A P I TA L M A R K E T S

on behalf of…

Healthcare’s Investment Bank

HealthiosXchange

12,000 InvestorsAcross (10)

Asset Classes in (37) Countries &2,000 Strategics in(46) Market sectors

“Seed-to-Exit”Direct

Investment

NO Adverse Selection

Messaging&

Notifications

Ratings & Reviews

Rules-BasedDeal Flow

Prediction & Sentiment Data

Proprietary Events

(6,000)+Growth

Companies

NO FeeNO Carry

Shorter “Exit”Horizons

Real-TimeValuations &

Research

Less Correlation

Reporting &Communications

ZeroUn-Invested

Capital

SHOWCASING THE PORTFOLIO

REDUCED FINANCING RISK

ADDITIONAL CARRIED INTEREST

GREATER FINANCING & “EXIT”CERTAINTY

SUPERIOR RETURNS

Healthcare’s Investment Bank

Showcasing the Portfolio

Healthcare’s Investment Bank

Reduced Financing Risk

Australia

North America

UAE & India

AsiaEurope & Middle East

Healthcare’s Investment Marketplace 6

Additional Carried Interest

Trading Lower Fees for Greater Carry

Source: Coller Capital, “Global Private Equity & Venture Barometer: Summer 2014”

Perf

orm

ance

Fees

Econ

omic

Envi

ronm

ent

Tran

spar

ency

Regu

latio

n

Liqu

idity

Vola

tility

Cons

olid

ation

Oth

er

0%

5%

10%

15%

20%

25%

30%

26%

22% 22%

15% 15%

11%

3%2%

15%

Prop

ortio

n of

Res

pond

ents

Healthcare’s Investment Bank

Greater Transaction Certainty & “Exit” Path

Healthcare’s Investment Bank

Greater Transaction Certainty & “Exit” Path

The actual number of

months before the next

transaction is 4. We predicted 3.

The actual value of the next transaction is $150 million and we predicted $150 million.

Healthcare’s Investment Bank

Superior Returns

12,000 InvestorsAcross (10)

Asset Classes in (37) Countries &2,000 Strategics in(46) Market sectors

“Seed-to-Exit”Direct

Investment

NO Adverse Selection

Messaging&

Notifications

Ratings & Reviews

Rules-BasedDeal Flow

Prediction & Sentiment Data

Proprietary Events

(6,000)+Growth

Companies

NO FeeNO Carry

Shorter “Exit”Horizons

Real-TimeValuations &

Research

Less Correlation

Reporting &Communications

ZeroUn-Invested

Capital

SUPERIOR RETURNS