Uni Qld Partner - Interflame

Presented by Jochen Mueller

UQ original outgoing plan

Researcher Type

Project Month(s)

Host Partner WP(s) Comments

ESR 30,31,32 UB 3,5,7 Sharing of best practice for air sampling and analysis of archived samples for delineation of

temporal trends

ER 21,22,23 UA 5,6,7 Analysis of archived samples for delineation of temporal trends and pharmacokinetic

modelling of human exposure

ER 16,17,18 SU 5,6,7 Analysis of archived samples for delineation of temporal trends and pharmacokinetic

modelling of human exposure

ER 27,28,29 VU 5,7 Analysis of archived samples for delineation of temporal trends

UQ original outgoing plan changes

Researcher Type

Project Month(s)

Host Partner WP(s) Comments

ESR 30,31,32

Not sure yet

UB 3,5,7 Sharing of best practice for air sampling and analysis of archived samples for delineation of

temporal trends

ER 21,22,23

Slightly later

UA 5,6,7 Analysis of archived samples for delineation of temporal trends and pharmacokinetic

modelling of human exposure

ER 16,17,18

Definitely Later

SU 5,6,7 Analysis of archived samples for delineation of temporal trends and pharmacokinetic

modelling of human exposure

ER

Change to ESR

27,28,29

MUCH EARLIER (16 – 18)

VU 5,7 Analysis of archived samples for delineation of temporal trends

Jake’s work at VU Amsterdam…

Key Aim: Assessment of per capita OPFR use/excretion through wastewater analysis

-Wastewater representative of population exposure

-Changes in population exposure can be estimated from changes in chemical loads in wastewater

Est. per capita OPFR contribution to wastewater in Australia (mg/day/1000 people)

COPFR *Flow

P*=

(CF)

The Hypothesis….

Samples

• 12 STPs around Census day

• Cover East Australia

• Correlate PCPPs etc with

population

Estimate per capita

consumption

- Apply approach to OPFRs- WW Sample Archive (since 2009)

Foon Yin Lai to Antwerp in 2014

- FR - metabolites in WW?

Jochen Stockholm (in European summer)

- Specific project ideas to be discussed- (Working with Fiona on PFC model)

Birmingham Secondment….

Neither specific topic nor ER or EST is clear

Healthy Humans in a Healthy Environment

finished

Jake’s work at VU Amsterdam…● Aim: conduct a per capita assessment of OPFR exposure in the

Australian population using raw wastewater samples collected on the 2011 Australian Census day

● Tasks: ● refine the extraction (SPE – Oasis MCX) method for OPFRs in wastewater so that only a small

sample volume is required (from 100mL to 1mL)

● Analyse the Australian wastewater samples

● Cross comparison between OPFRs measured on GC-MS (EI) and LC-MSMS (ESI) in the same samples Compare measured loads of OPFRs in wastewater against the population size to determine per capita exposure and ideally identify regional differencesb

● In addition I’ve also been working on the extraction and analysis of carbamate pesticides and their metabolites in breast milk,  di-2-ethylhexyl phthalate extraction from swabs, have been learning the GCMS and over the next few weeks hope to have an introduction on the microTOF.

● I want to get some more writing done over the next few days for this confirmation document and then maybe we have a chat?