Treatment Advances in Achieving Remission in Mild to

Moderate Ulcerative Colitis

Goals of Therapy for Patients With UC

Sequential Therapies for UC

Oral 5-ASA Formulations: Sites of Delivery

Conventional Corticosteroids in UC

Corticosteroids: Dependency—Short- and Long-term Efficacy

CORE I and II: Budesonide MMX Primary End Point: Combined Clinical and Endoscopic

Remission

Azathioprine vs 5-ASA for Corticosteroid-Dependent, Active

UC

Anti-TNF Therapies for Moderate to Severe Disease

Treatment Algorithm to Maximize Remission and Minimize

Corticosteroid Dependence in UC

Patient Case

Mesalamine Safety

Patient Case (cont)

Pooled Safety Data: Adverse Effects of Budesonide MMX in Patients With Active UC

Anti-TNF Agents: Adverse Events

Minimizing Toxicity for Anti-TNF Therapy

Summary: Safety

Effect on Bone Density

Monitoring the Patient Receiving Budesonide MMX

Summary: Safety of Agents Used to Induce Remission in Mild to

Moderate UC

Abbreviations

References

References (cont)

References (cont)