Transcript of The lymphatic organs 2
- 1. The lymphatic organs Dr. Samar AskerDr. Samar Asker
- 2. The spleen Single intra abdominal hemo lymphatic organ. To
filter the blood from any organism
- 3. a- Capsule: Thick C. T. formed of fibroblast collagen &
elastic fibers containing smooth muscle fibres. Is covered by
peritoneum. Stroma:
- 4. b-Trabeculae: They arise from the hilum of spleen may be
from the capsule . Formed of Thick C. T. containing smooth muscle
fibres. Divide the spleen into irregular compartments. The capsule
and trabeculae contain blood vessels and nerves.
- 5. Reticular CT : formed of cells & fibres in the
bacheground stained only with silver{Ag} stain.
- 6. Parenchyma In fresh sections it shows white spots on red
background i.e devided into: White pulp & red Pulp
- 7. White pulp= (Malpighian corpuscle): Rounded or oval
scattered follicles with an arteriole on one side called central
arteriole or follecular arteriole. Formed of reticular CT in which
cells are arranged around the arteriole into 4 concentric
zones:
- 8. 1.Thymus dependent zone: periarterial lymphatic sheath
(PALS) contain T- lymphocytes around the central arteriole
2-Germinal center: pale area contain activated large B lymphocytes,
plasmablasts, plasma cells & macrophages.
- 9. Follicular zone= corona: dark contain B lymphocytes Marginal
zone : at the periphery contain: T& B lymphocytes plasma cells
& macrophages.
- 10. Red Pulp: Formed of : Splenic cords Blood sinusoids.
- 11. Splenic cords= Billroth cords The areas between the white
pulp & bl. Sinusoids contain blood cells: (RBCs, WBCs
,lymphocytes , monocyts) plasma cells Macrophage.
- 12. Blood sinusoids. Irregular blood spaces lined with
fenestrated endothelial cells & non- continuous basement
membrane For easy passage of blood cells to the blood. Macrophages
appear in the wall of the sinusoids to engulf any foreign
bodies
- 13. Filtration Formation Storage DestructionBlood Functions
Immuonological
- 14. Functions 1. Filtration of blood from any organism by
macrophages 2. Formation of blood cells : in embryo &
lymphocytes in germinal center 3. Storage of blood cells &
platelets. 4. Destruction of RBCs& storage of iron. 5.
Immuonological function the reticular cells trap the antigen &
present it to lymphocytes---- humeral & cell mediated
immunity.
- 15. Lymph node spleen number multiple Single Function Filterati
on of lymph Immunit y Filtration & stores of blood
Immunity
- 16. Lymph node spleen Capsule Thin, covered with fat Smooth ms
only at hilum., Thick covered with peritoneum rich in smooth muscle
Trabeculae Thin arise from the capsule Thick arise from the
hilum
- 17. Lymph node spleen Parenchy ma Cortex & medulla Cortex =
lymph follicle & lymph sinus The follicles have no arteriol.
Medulla = Medullary cords & Medullary sinuses. White pulp &
red pulp White pulp = lymph follicle no sinuses. The follicle
contain arteriole. Red pulp = splenic cords & blood sinusoids.
Cells lymphocytes + macrophages + plasma. macrophages + plasma
cells + WBCs +RBCs
- 18. Tonsils Partially capsulated lymphatic tissue 3 sites:
Palatine tonsils Lingual tonsil Pharyngeal Tonsil
- 19. Palatine tonsilsPalatine tonsils Two oval masses ofTwo oval
masses of lymphatic tissue under thelymphatic tissue under the
mucous membrane of oro-mucous membrane of oro-
pharynx.pharynx.
- 20. Lymphatic tissue of two kinds: Lymph follicle with or
without germinal center Diffuse lymphatic tissue: Lymphocytes
plasma cells macrophage.
- 21. Each tonsils is coveredEach tonsils is covered withwith
stratified squamous epitheliumstratified squamous epithelium which
dips into the underlyingwhich dips into the underlying lymphatic
tissue to crypts.lymphatic tissue to crypts.
- 22. mucous glandsmucous glands deep to thedeep to the
folliclefollicle theirtheir ducts open toducts open to the surface
&the surface & not in the basenot in the base of the crypt
soof the crypt so inflammation isinflammation is commoncommon
- 23. Incomplete capsule: separates the tonsils from the
underlying structure. Salivary corpuscle: Lymphocyte which pentrate
the epith. To appear in the
- 24. Lingual tonsil: At the base of the tongue Secondary
follicle & diffuse lymphatic. Non keratinised str. Sqam.epth
which form crypt. mucous glandsmucous glands openopen into the base
of the crypt.into the base of the crypt.
- 25. Pharyngeal Tonsil Single mass of lymphoid tissue under
nasopharynex. Covered with pseudo stratified columnar ciliated
epith. with goblet cells Folded with no crypt Function :at the
beginning of the respiratory &digestive systems so protect from
bacteria & produce Ab.
- 26. Medium sized artery & vein
- 27. Lymph node
- 28. The spleen
- 29. central arteriole
- 30. Palatine tonsilsPalatine tonsils