Post on 16-Jan-2017
The ECDC public health microbiology programme 2015-16
14th National Microbiology Focal Points meeting
Marc Struelens, Chief Microbiologist on behalf of
Microbiology Coordination Section, Office of the Chief Scientist European Centre for Disease Prevention and Control14th NMFP, Stockholm, 12-13 May 2016
Microbiology Coordination Team
Marc Struelens - Chief Microbiologist, Head of Section
Amanda Ozin - Senior Expert Microbiology
Katrin Leitmeyer - Senior Expert Virology
Barbara Albiger - Expert Microbiology
Joana Revez - Scientific Officer
Signe Gilbro - Communication Officer Web and Social Media
Milka Docheva - Secretary
ECDC Strategic Multi-annual Programme 2014–20 Microbiology support
By 2020, ECDC has achieved:
• Consolidation of the capacity of the EU public healthmicrobiology system for European surveillance and epidemicpreparedness;
• Implementation of a system that assists Member States inmonitoring critical microbiology capabilities;
• Gradual integration of selected molecular typing data intoEuropean surveillance and epidemic investigations forpriority diseases;
• Further integration of EU clinical and public healthlaboratories in the surveillance and alert systems for humanand zoonotic pathogens
ECDC Microbiology support: weaknesses and recommendations from external evaluation
Weaknesses/challenges Recommendations
• Least known/appreciated area of ECDC work
• Communication on outputs and added value• Consider reorganisation of microbiology
outside of the disease programmes
• Credibility gap • More microbiology expert staff• Stronger coordination of DP microbiology
support by “micro unit”
• Mixed views on added value • Analysis and demonstration of added value
• Polarised MS views on molecular typing
• Ensure synergy with TESSy data analysis
• Fast moving diagnostic technology, WGS
• Perform technology assessment, cost-effectiveness analysis, guidance and pilot implementation projects
Source: The second independent evaluation of the ECDC in accordance with its Founding Regulation (European Parliament and Council Regulation (EC) no 851/2004. FINAL REPORT October 2014)
ECDC supported laboratory network activities, 2015 (N=12 network/projects*)
Source: ECDC Director Annual Report 2015
• *laboratory networks managed by ECDC Disease Programmes and two advisory committees (MSTF, EUCAST)
Type of work No. of outputs
External quality assessment 7
Technical guidance 8
Laboratory training courses 9
Technical capacity mapping 7
Cross-border testing services 6
Outbreak investigation support 3
First EULabCap report
Source: http://ecdc.europa.eu/en/publications/Publications/EU-laboratory-capability-monitoring-system-2013.pdf
Critical review of the draft report at the NMFP13/AF42 joint meeting in May 2015.
Integration of advice on: - Main conclusions- Publication format to
enable benchmarking.
Published February 2016.
Communication and consultations
Newsletter
• Project updates
• Publications, upcoming events
Extranet
• Documents for written consultation/for information
Webportal
• New microbiology page with repository of EQA
• New: capacity mapping reports/ resources
ECDC Joint Strategic Meeting September 2015 –conclusions on molecular typing
• ECDC to consolidate ongoing molecular typing forsurveillance and prioritise those pathogens/diseaseswhere it is possible to demonstrate EU public healthbenefits.
• Molecular typing for EU surveillance should undergo astepwise transition to WGS, based on continuous updateon cost, performance and assessment of public healthvalue.
• Take into account both ECDC resources and mapping ofnational capacities. ECDC should continue supportingtraditional typing methods.
Roadmap - V1.2, 2013 for integration of molecular and genomic typing into European level surveillance and epidemic preparedness
2013
Concept paper: Surveillance of communicable diseases in Europe – a concept to integrate molecular typing data into EU-level surveillance. Stockholm ECDC; 2013.
2007
2016WGS Strategy and Roadmap - V2.1, 2016-19
• Co-drafted and peer-reviewed by ECDCDiseases programmes
• Prioritised in consultation with MSTF,November 2015
• Approved internally January 2016
• Submitted for written comments to theAdvisory Forum AF 44 – February 2016
• 6 comments (Belgium, Norway, Spain,Sweden, European Commission,WHO/Europe)
• Expected publication: June, 2016
ECDC roadmap for integration of molecular and genomic typing into European level surveillance and epidemic preparedness- version 2.1, 2016-19
Communication and consultations
Meetings and expert consultations
• 22-24 September 2015 - Joint Strategic Meeting
• 19 November 2015 - WGS strategy at EU level
• 20 November 2015 - MSTF Typing Roadmap prioritisation
Surveys
• June- September 2015: National capacity/plans for WGS
• October 2015: EULabCap 2014 data call and validation
• February 2016, May 2016: ZIKV diagnostic capability
European Commission- ECDC collaboration on reference laboratories, 2015-16
• EMERGE Joint Action
Collaboration on Ebola technical guidance with QUANDHIP, ENIVD,and the European Mobile Laboratories
ECDC Observer and Advisor to the EMERGE network
Coordination and communication with ENIVD/ EVD-LabNet
• ECDC contribution to CHAFEA study on ‘Cost-benefit analysisof reference laboratories for human pathogens’
Expert workshops
Study data collection (EU lab networks as case studies)
Draft report review
Scientific advice on microbiology RTD projects, 2015-16
ECDC expert contributions/advice to:
• PathNGenTrace• PREMEDICS• PREPARE• COMPARE• GMI
International conferences
• IMMEM X, March 2016
• 26th ECCMID, April 2016
• EBSA Conference, April 2016
• RAMI-NGS Conference, June 2016