SMALL INTESTINE TUMORS Benign Epithelial Tumors Malignant Epithelial Tumors Lympho- proliferative...

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Transcript of SMALL INTESTINE TUMORS Benign Epithelial Tumors Malignant Epithelial Tumors Lympho- proliferative...

SMALL INTESTINE TUMORS

BenignEpithelialTumors

MalignantEpithelialTumors

Lympho-proliferative

disorders

MesenchymalTumors

BrunnerGland

Lesions

BenignIntestinal

polypi

T cell B cell

GISTGISTFatty

tumorsNeuraltumors

Paragangl.

Smooth Ms

tumorsVasc.

tumors

•Lipoma•Liposarcoma

• Gut autonoic tumor• Schwannoma• Neurofibroma• Granular cell tumor

• Leioyomayoma• Leioyomayosarcoma

• Haemangioma• Angiosarcoma• Lymphangioma• Kaposi sarcoma

•Benign•Malignant

Enteropathyassociated

T-cell lymphoma

•Diffuse large cell lymphoma.•Small non cleaved cell lymphoma.•MALT cell lymphoma.•Mantle cell lymphoma.•Immuonoproliferative small cell disease

•Pr. ADC•Metastasis.•Carcinoid.

•Adenomas•Hamartomas

Adenoma Leiomyoma Angioma

Lipomas others

Adenocarcinoma Lymphom

as

Leiomyosarcomas

others

Carcinoid Tumors

Adenoma in duodenum

A, Film from an enteroclysis demonstrating a smooth, submucosal lesion that was found to

be lipoma (arrow). B, Surgical resection specimen of a lipoma from another patient who presented with intussusception and

bleeding

CT scan of the lower abdomen demonstrates a soft tissue mass of fat density in the lumen of the terminal ileum (arrow). These characteristics are diagnostic for a lipoma

Small bowel follow through examination demonstrates a smooth, well-circumscribed mass arising from the wall of the terminal ileum. The appearance is consistent with a benign mesenchymal tumor, such as a lipoma or a carcinoid tumor

Small bowel follow through examination shows a polypoid eccentric mass arising from the wall of the terminal ileum (arrow).

Small bowel follow through examination demonstrates a circumferential apple- core lesion of the jejunum (arrow), producing distension of the proximal small bowel.

S.I. ADENOCARCINOMA

Film from a small bowel follow through demonstrating an “apple-core” appearance caused by a metastatic lesion to the small intestine from a scirrhous gastric cancer.

Upper gastrointestinal endoscopy shows a duodenal adenocarcinoma in the second portion of the duodenum in a patient who presented with heme positive stool. The mass occupied approximately 50 percent of the diameter of the duodenum. The thick erythematous folds in the upper half of the image distinguish the lesion from the pale, thin folds of the normal tissue in the lower half.

Contrast examination of the small intestine in a patient with partial small bowel obstruction and extensive extramucosal disease caused by metastatic lung cancer.

Small bowel follow through study shows multiple rounded, nodular filling defects in the wall of the small bowel (arrows). Multiple small bowel tumors may be seen in metastatic disease or in polyposis syndromes; the most common cause of small bowel metastases is melanoma.

primary intestinal

lymphoma

Involvement of the intestine by a lymphoid malignancy extending from involved

retroperitoneal or mesenteric lymph nodes

Barium enema shows a large soft tissue mass in the cecum (arrows) caused by intussusception of a lymphoma arising in the terminal ileum

CT scan of the abdomen demonstrates a large mass in the lumen of a distended loop of small bowel. Note mesenteric fat in the center of this intraluminal mass (arrow).

The use of oral antibiotics such as tetracycline appears to be beneficial in the early phases of the disorder, suggesting a possible infectious etiology. Combination chemotherapy has been administered during later stages of the disease, with variable results

Carcinoid tumors arise from argentaffin cells of the crypts of Lieberkühn and are found from the distal duodenum to the ascending colon, areas embryologically derived from the midgut. More than 50% of intestinal carcinoids are found in the distal ileum, with most congregating close to the ileocecal valve. Most intestinal carcinoids are asymptomatic and of low malignant potential, but invasion and metastases may occur, leading to the carcinoid syndrome

S.I. CARCINIOD

CT scan demonstrates a soft tissue mass containing coarse central calcifications (short arrow) in the right lower quadrant. This carcinoid tumor is producing a characteristic desmoplastic response with spiculation of the adjacent mesenteric fat (long arrow).

Capsule endoscopy view of an ulcerated mass in a patient who presented with gastrointestinal bleeding. Four ulcerated, bleeding masses were found throughout the small bowel; these were confirmed at surgery and found to be sarcomas