Homework from last class:Homework from last class: Complete the Mitosis, Stages of the Cell Cycle,

and The Cell Cycle worksheets from the handout Study for Quiz on Ch. 5.1 – The Cell Cycle and

Mitosis (pp. 150-157) Inform me of your Mitotic Movies group Bring field trip forms and $ Read over class notes and check out the class

blog: http://msoonscience.blogspot.com/

Ch. 5.1 QuizCh. 5.1 QuizYou have ~7 minutes to write the quiz.

Good luck!

Field Trip – March 1Field Trip – March 1UBC Michael Smith LabsUBC Michael Smith Labs Meet in front of the UBC Bookstore at 8:45am We will walk to the Michael Smith Labs together

(right beside UBC Bookstore)

Cytokinesis, Checkpoints in Cytokinesis, Checkpoints in the Cell Cycle, and Cancerthe Cell Cycle, and CancerChapter 5.1 pp. 158-161

CytokinesisCytokinesiscytokinesis: the final stage of the cell cycle; separates the 2 nuclei and cell contents into 2 daughter cells. New cells are identical to the parent cell.

Parent cell (in telophase)

2 identical daughter cells

Animal cells – cell membrane pinches together to divide the cell’s cytoplasm and organelles

Plant cells – a cell plate forms along the centre of the cell to divide the cell into 2 daughter cells

Checkpoints in the Cell CycleCheckpoints in the Cell CycleActivities in the cell cycle are monitored and controlled at specific stages (checkpoints).

Proteins at these checkpoints monitor cell activities send info to nucleus instructs the cell whether or not to divide

Cells will not divide if: Not enough nutrients to support cell growth DNA in nucleus has not been replicated DNA is damaged

Checkpoints in the Cell CycleCheckpoints in the Cell Cycle

p. 159

Control of the Cell CycleControl of the Cell Cyclehttp://nobelprize.org/educational/medicine/2001/cellcycle.html

Activity time!Group 1: Onion Root Lab Activity

Group 2: Cancer Investigation

Activity Instructions:Activity Instructions: I will divide you into 2 groups.

Group 1 will begin with the Onion Root Lab activity at the back of the class.

Group 2 will begin with the Cancer Investigation at the front of the class.

After 20 minutes, the groups will switch activities.

Complete your worksheets at each station.

CancerCancer Checkpoints in the cell cycle can stop the cell from

growing and dividing.

Mutagens (ex. viruses, X rays, UV light, chemicals) can cause mutations in a cell and harm the organism.

If a mutation occurs in a gene producing the instructions for a checkpoint protein, cell cycle control will be lost can lead to uncontrolled division (cancer)

Healthy cells stop dividing when they receive messages from neighbouring cells; cancer cells do not respond to messages from nearby cells continue to divide tumour

p. 161

Cancer cells are not specialized, but release chemicals to attract small nearby blood vessels branch into the tumour to deliver nutrients feed tumour tumour growth

Cancer can spread to other parts of the body if some tumour cells break away carried by the blood vessels to a new location can form another tumour

Cancer cells have large, abnormal nuclei because cell division checkpoints no longer function chromosomes do not divide correctly

Cancer AnimationsCancer Animationshttp://science.education.nih.gov/supplements/nih1/cancer/activities/activity2_animations.htm

Homework for next class:Homework for next class: Complete the Onion Root Lab Activity and The

Cell Cycle and Cancer worksheet (if not already completed)

Read notes on Cancer on the class blog (in this slideshow)

Keep working on your Mitotic Movies project Bring field trip forms and $ ASAP Read over class notes and check out the class

blog: http://msoonscience.blogspot.com/

Have a great weekend!

Works CitedWorks CitedImages taken from the following sources:http://www.biologyreference.com/Co-Dn/Cytokinesis.htmlhttp://www.phschool.com/science/biology_place/labbench/lab3/cytokin.htmlhttp://www.nccs.com.sg/kac/abcs/detect.htmhttp://www.phd7.idaho.gov/Infectious%20Disease/infectiousdiseasemain.htmlhttp://www-ipcms.u-strasbg.fr/spip.php?article647http://science.education.nih.gov/supplements/nih1/cancer/activities/activity2_animations.htmhttp://www.microscopy-uk.org.uk/micropolitan/botany/frame4.html