Salivary acini

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Salivary Acini

BySecond year studentsSection (4) Group (c)

Under supervision of

Dr/Azza El-Hadidi Dr/Sanaa El-Sherbeni Dr/Ghalia Mahfouz

Salivary Gland

Second Year Section 4 2009/2010

What is the salivary gland?

Simple or compound branched tubuloalvealar gland

Second Year Section 4 2009/2010

Types

Major♥ Submandibular♥ Sublingual♥ Parotid

Minor♥ Buccal♥ Labial♥ Palatine♥ Lingual

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Function Secretion of saliva

Second Year Section 4 2009/2010

structure

Second Year Section 4 2009/2010

stroma

1- Connnective tissue

2- Trabeculae

3- Reticular fibers

Parenchyma 1.Secretory part (salivary acini)

2. Transport system (branching ducts)

Second Year Section 4 2009/2010

Model of the gland: a bunch of grapes: berry= acinusModel of the gland: a bunch of grapes: berry= acinus

stalk of berry: intercalated ductstalk of berry: intercalated duct

Salivary Acini

Second Year Section 4 2009/2010

What is the salivary acini? It the secretory part of

salivary gland

Second Year Section 4 2009/2010

Structure

The salivary acini is composed of a group of secretory cells that surround a central lumen leading to the duct system.

The acinus is surrounded by a basement membrane.

There are branching myoepithelial cells,(basket cells) their contraction squeezes the secretions into the duct.

Second Year Section 4 2009/2010

Classification

According to the nature of secretion

There are 3 types:

Mucous Serous mucoserous

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Mucous acinus

LM Has wide lumen Surrounded by numerous basket cells Secretory cells are cuboidal with distinct

boundries Nucleus is basal flat Cytoplasm is pale foamy

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Basket cellBasket cell

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

EM

Cytoplasm contains: rER and mitochondria in the basal part Supranuclear golgi appartus Apical electron lucent mucous granules

Second Year Section 4 2009/2010

Electron lucent

Granules

Second Year Section 4 2009/2010

Serous acinus

LM Dark in staining Has narrow lumen Surrounded by less numerous basket cells Secretory cells are pyramidal with indistinct

boundaries Central rounded nucleus Deep basophilic cytoplasm Apical acidophilic zymogen granules

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

EMCytoplasm contains: Numerous rER and mitochondria in the

around nucleus Supranuclear golgi appartus Apical electron dense secretory granules

Second Year Section 4 2009/2010

Electron denseGranules

Why Crying??

Histology is Easy!!

Mucoserous acinusmixed acinus

Is mainly mucous Surrounded by group of serous cells

called serous demilune or crescent of gianuzzi

Secretion of serous cells passes into canaliculi between mucos cells and lumen of the acinus

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Mucous cellMucous cell

Crescent ofCrescent ofgianuzzigianuzzi

Basket cellBasket cell

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

Important MCQ question

? ? ? ?

1- Mucous acini are lined by cells having

a) Apical zymogen granulesb) Basal rounded nucleic) Indistintinct lateral boundariesd) Ion transport activity e) Non of the aboveAnswer e

Second Year Section 4 2009/2010

2- basket cells are

a) secretory cells

b) Contractile cells

C) endocrine cells

D) connective tissue cells

e) sensory receptor

Answer b

Second Year Section 4 2009/2010

3- serous acini are a) dark in staining b) surrounded by basket cellsc) lined by pyramidal cells with apical

zymogen granulesd) all of the above e) non of the above

Answer d

Second Year Section 4 2009/2010

Second Year Section 4 2009/2010

See you in See you in

another another

presentatiopresentatio

nn

Second Year Section 4 2009/2010