Paul van der Schoot

Virus Assembly and the Topology of ssRNA

deskeng.com/articles/aaahnd.htm Konecny et al. Biopolymers 82 (2006) 106

ARMs

CPs

cavity

in vitro encapsulation: • native ss RNAs• foreign ss RNAs• ds DNA• synthetic polyanions• nanoparticles

Roya Zandi

Qd

dlR

d

dM

g

g

12

1

12

1~

2

*

Yoffe et al. PNAS 105 (2008), 16153

Are viral RNAs special?

branching

capsid size charges on ARMs

solvent quality

Flory theory:

Gopal et al. preprint (2011)

RNA viral 54

RNA random 3

branchedrandomly4

linear2

g

g

g

g

d

d

d

d