IMPLICATION FOR PRACTICE

Recommending the daily use of meridol® Parodont Expert toothpaste signifi cantly reduces plaque in patientswith gingivitis.

• meridol® Parodont Expert provides signifi cantly greater plaque reduction compared to a regular fl uoride

toothpaste after 3 weeks and 3 months

• This proves the superior anti-bacterial e� cacy of meridol® Parodont Expert toothpaste in a long-term clinical study

RESULTS

1.80 –

1.60 –

1.40 –

1.20 –

1.00 –

0.80 –

0.60 –

Mea

n Pl

aque

Inde

x

CLINICAL STUDY ESSENTIALS

• double blind, randomised, parallel group study

• 237 participants with gingivitis completed the study

• 3 month study duration

• Performed at the Universitätsklinikum Carl Gustav Carus an der TU Dresden, Poliklinik für Parodontologie, Dresden, Germany

• Data on fi le

negative control

(NaMFP)

baseline after 3 weeks

>50%plaque reduction

after 3 monthsonly relevant data shown

* p<0.001 vs. baseline• p<0.05 vs. NaMFP toothpaste

* •

*

* •

*

meridol® Parodont Expert Toothpaste:Plaque-reducing e� cacy proven in gingivitis patients

meridol® Parodont

Expert

meridol® Parodont

Expertmeridol® Parodont

Expert

Antibacterial e� ect (= reduction of Mean Plaque Index) was measured after twice daily usage of toothpastes in gingivitis patients:

YOUR PARTNER IN ORAL HEALTH

www.colgateprofessional.co.uk

negative control

(NaMFP)

negative control

(NaMFP)

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SUPPLEMENTARY REVIEW INFORMATION

CONCLUSION

meridol® Parodont Expert toothpaste is signifi cantly more e� ective in reducing plaque comparedto a regular fl uoride toothpaste in patients with gingivitis after 3 weeks and 3 months.

STUDY PARTICIPANTS

240 participants (83 male and 157 female) aged 18 – 65 years with gingivitis.

METHODS

Plaque index (PI, according to Silness and Loe 1964), Gingival Index (GI, according to Loe 1967), andModifi ed Sulcus Bleeding Index (mSBI, according to Mühlemann and Son 1971) were assessed todetermine plaque, gingivitis, and bleeding, respectively.

PRODUCTS UNDER INVESTIGATION

• Control group: toothpaste with 1.400 ppm F- from sodium monofl uorophosphate toothpaste (NaMFP), meridol® toothbrush

• Test group: meridol® Parodont Expert toothpaste with 1.400 ppm F- from amine fl uoride, meridol® toothbrush

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of local product URL

TRIAL PROCEDURE

1. Baseline examinations of PI, GI, and mSBI

2. All participants were randomly assigned to control and test group.

3. Participants were instructed to brush twice daily for 2 minutes with the allocated toothpaste and toothbrush at home.

4. Clinical assessments were performed after 3 weeks and 12 weeks (= 3months).

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