The Future of Biology & Medicine is All About Computers

Philip E. Bourne PhDphilip.bourne@nih.gov

Computers an Ever Powerful Tool

1974

1960’s

1981Today

The Human Genome

• Took at least 10 years and several $bn

• Biology’s equivalent of landing on the moon

• Genome now costs $1000

Proteins and You

HIV Protease

Hemoglobin

Common Cold Virus

Ribosome

Prion

Studying Iron Metabolism

Some Things Stay with You Your Whole Life

Num

ber o

f rel

ease

d en

tries

Year

The Growth of Data is A Major Driver in Biology

Why are there so many different shapes?

Big Data

Other ‘Omic

Imaging Phenotypic

Clinical

Genomic

Exposure

An Example of That Potential:The Story of Meredith

http://fora.tv/2012/04/20/Congress_Unplugged_Phil_Bourne

Josh Sommer – A Remarkable Young ManCo-founder & Executive Director the Chordoma Foundation

http://sagecongress.org/Presentations/Sommer.pdf

“And that’s why we’re here today. Because something called precision medicine … gives us one of the greatest opportunities for new medical breakthroughs that we have ever seen.”

President Barack ObamaJanuary 30, 2015

Precision Medicine

Being a Scientist is a Great Life