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in-ADME ResearchpCEL-X Rev 3.1

Overview1. Atenolol Caco-2 Refinement

2. Amitriptyline Caco-2 Simulation

3. Amitriptyline in situ brain perfusion Refinement

4. BD Pre-coated PAMPA Plates Leak

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Caco-2 Refinement Example

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Simulation Example

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Refinement of in situ Data

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BD Pre-Coated PAMPA Plates

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Thin Membranes Leak Water & Can’t be Stirred

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Thin Membranes Leak Water & Can’t be Stirred

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Thin Membranes Leak Water & Can’t be Stirred

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Thin Membranes Leak Water & Can’t be Stirred

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