Improved Fine Needle Aspiration Biopsy

Team: Janie Goldsworthy, Kristi Hinner, Nick Kortan, Crystal MarshekClient: Dr. Elizabeth BurnsideAdvisor: John Webster

Problem Statement

GOAL: To modify the needle used during a Fine Needle Aspiration (FNA) procedure. The modification should not drastically change the FNA procedure and still increase the amount of tissue removed for cytological testing. It should also minimize the time (by collecting an adequate sample size on the first attempt) and discomfort caused to the patient during the procedure.

What is FNA?

Technique used to extract cells; no incision neededSeveral insertions are usually required to ensure an adequate sample sizeSamples are sent to pathologist to be analyzed National Breast Cancer Center,

http://www.NBCC.org

Fine Needle Aspiration (FNA)

A.D.A.M., http://www.adam.com

Product Design Specifications

Removes adequate number of cells for diagnosis. Should not cause more discomfort than current FNA procedure. Constrained to standard 20-25-gauge needle, client prefers 23-gauge.

Micro-Drill Bit Insert

Draws cells up drill fluting into needleFits inside 23-gauge needle Outer Diameter: 0.0145 inches

Currently too short Length: approximately 1 inch Needs to be lengthened

Easy to obtain

Needle Manufacturer

Drill Bit ContactsResponsesWork in Progress

ME Shop/Process

WeldingSolderingBrazing

Sample Size

Comparison Old vs. New Techniques

Histological analysisCell Quantification

Testing

Tissues AvailableFuture Testing

Future Work

Prototype developmentResearch into appropriate materials to be used (stainless steel, Co-Cr, Ti)Develop protocol for quantifying testingTest on tissue similar to breast tissueQuantify sample needed for cytological evaluation