Imaging the Misshapen Head

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Imaging the Misshapen Head. David Nielsen, MD Pediatric Radiologist. Imaging the Misshapen Head. Objective: Better understand how to image the most common causes of a misshapen head. Imaging the Misshapen Head. Common causes: Macrocephaly Microcephaly Craniosynostosis - PowerPoint PPT Presentation

Transcript of Imaging the Misshapen Head

Imaging the Misshapen Head

David Nielsen, MDPediatric Radiologist

Imaging the Misshapen Head

• Objective:

– Better understand how to image the most common causes of a misshapen head

Imaging the Misshapen Head

• Common causes:– Macrocephaly– Microcephaly– Craniosynostosis– Posterior plagiocephaly

Imaging the Misshapen Head

• Common causes:– Macrocephaly– Microcephaly– Craniosynostosis– Posterior plagiocephaly

Macrocephaly• Definition:

– Macrocephaly = Macrocrania

Macrocephaly• Definition:

– Macrocephaly = Macrocrania

– Head circumference > 2SD (> 95%) above the mean for age, sex, race, and gestation

What is the most common imaging finding in

macrocephaly?

A. B. C. D.

0% 0%0%0%

A. HydrocephalusB. Benign Enlarged

Subarachnoid Spaces (BESS)

C. Subdural HematomaD. Intracranial Mass

Macrocephaly• Ddx:

– #1: Benign Enlarged Subarachnoid Spaces (BESS)

– Also called:• Benign macrocrania• Benign extra-axial

collections• Benign external

hydrocephalus• Transient communicating

hydrocephalus

NL

BESS

Macrocephaly

• Benign enlarged subarachnoid spaces– Clinical:

Macrocephaly

• Benign enlarged subarachnoid spaces– Clinical:

• Macrocephaly presents between 3-6 months and peaks at about 7 months

Macrocephaly

• Benign enlarged subarachnoid spaces– Clinical:

• Macrocephaly presents between 3-6 months and peaks at about 7 months

• May have family history of macrocephaly

Macrocephaly

• Benign enlarged subarachnoid spaces– Clinical:

• Macrocephaly presents between 3-6 months and peaks at about 7 months

• May have family history of macrocephaly• Normal developmental/neurological exam

Macrocephaly

• Benign enlarged subarachnoid spaces– Clinical:

• Macrocephaly presents between 3-6 months and peaks at about 7 months

• May have family history of macrocephaly• Normal developmental/neurological exam• Stabilizes by 18 months along a curve paralleling the

95% curve

Macrocephaly

• Benign enlarged subarachnoid spaces– Clinical:

• Macrocephaly presents between 3-6 months and peaks at about 7 months

• May have family history of macrocephaly• Normal developmental/neurological exam• Stabilizes by 18 months along a curve paralleling the

95% curve• Spontaneously resolves by 24-36 months

Macrocephaly

• Benign enlarged subarachnoid spaces– Imaging:

Macrocephaly

• Benign enlarged subarachnoid spaces– Imaging:

• Symmetrical enlargement over the frontoparietal convexities and within the interhemispheric fissure, cortical sulci, and sylvian fissures

Macrocephaly

• Benign enlarged subarachnoid spaces– Imaging:

• Symmetrical enlargement over the frontoparietal convexities and within the interhemispheric fissure, cortical sulci, and sylvian fissures

• No mass effect

Macrocephaly

• Benign enlarged subarachnoid spaces– Imaging:

• Symmetrical enlargement over the frontoparietal convexities and within the interhemispheric fissure, cortical sulci, and sylvian fissures

• No mass effect• Same imaging characteristics as CSF

Macrocephaly

• Benign enlarged subarachnoid spaces– Imaging:

• Symmetrical enlargement over the frontoparietal convexities and within the interhemispheric fissure, cortical sulci, and sylvian fissures

• No mass effect• Same imaging characteristics as CSF• Cortical veins course through the fluid

Macrocephaly

• Benign enlarged subarachnoid spaces– Imaging:

• Symmetrical enlargement over the frontoparietal convexities and within the interhemispheric fissure, cortical sulci, and sylvian fissures

• No mass effect• Same imaging characteristics as CSF• Cortical veins course through the fluid• Ventricles are normal or mildly enlarged

Cortical veins

Benign enlarged subarachnoid spaces

Macrocephaly

Macrocephaly

Benign enlarged subarachnoid spaces

Cortical veins

Macrocephaly• Ddx:

– #1: Benign Enlarged Subarachnoid Spaces (BESS)

– Other:• Hydrocephalus (HC)• Subdural hematoma• Intracranial mass (rare)• Congenital/

syndromic/metabolic (rare)

Macrocephaly

Clinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT (or MRI)

Developmentally abnormal with open or closed fontanel

MRI

• Imaging is based on development and fontanel/age:

Macrocephaly

Clinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT (or MRI)

Developmentally abnormal with open or closed fontanel

MRI

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

• Normal neurological exam with open fontanel

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

• Normal neurological exam with open fontanel– Short-term clinical follow-up with serial head

circumference measurements with or without ultrasound

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

• Normal neurological exam with open fontanel– Short-term clinical follow-up with serial head

circumference measurements with or without ultrasound• If head stabilizes (i.e. measurements again parallel the normal

curve), the likely diagnosis is BESS:

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

• Normal neurological exam with open fontanel– Short-term clinical follow-up with serial head

circumference measurements with or without ultrasound• If head stabilizes (i.e. measurements again parallel the normal

curve), the likely diagnosis is BESS:– No imaging (or no additional imaging) is recommended

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

• Normal neurological exam with open fontanel– Short-term clinical follow-up with serial head

circumference measurements with or without ultrasound• If head stabilizes (i.e. measurements again parallel the normal

curve), the likely diagnosis is BESS:– No imaging (or no additional imaging) is recommended

• If head continues to enlarge disproportionate to the child’s growth (i.e. measurements do not again parallel the normal curve) and clinical exam is still otherwise normal:

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

• Normal neurological exam with open fontanel– Short-term clinical follow-up with serial head

circumference measurements with or without ultrasound• If head stabilizes (i.e. measurements again parallel the normal

curve), the likely diagnosis is BESS:– No imaging (or no additional imaging) is recommended

• If head continues to enlarge disproportionate to the child’s growth (i.e. measurements do not again parallel the normal curve) and clinical exam is still otherwise normal:

– Ultrasound to screen for severe hydrocephalus or large mass

Benign enlarged subarachnoid spaces

Macrocephaly

Macrocephaly

Choroid plexus papilloma

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT (or MRI)

Developmentally abnormal with open or closed fontanel

MRI

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT (or MRI)• Normal neurological exam with closed fontanel

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT (or MRI)• Normal neurological exam with closed fontanel

– Case-by-case risk/benefit assessment of short-term clinical follow-up with serial head circumference measurements versus imaging with CT (radiation risk) or MRI (sedation risk)

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT (or MRI)• Normal neurological exam with closed fontanel

– Case-by-case risk/benefit assessment of short-term clinical follow-up with serial head circumference measurements versus imaging with CT (radiation risk) or MRI (sedation risk)

– Each modality also has advantages for the clinical question to be answered (e.g. CT is preferred for bones)

Macrocephaly

Benign enlarged subarachnoid spaces

6 mo 11 mo

Macrocephaly

Pilocytic Astrocytoma

MRI - Benign enlarged subarachnoid spaces

Macrocephaly

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT (or MRI)

Developmentally abnormal with open or closed fontanel

MRI

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT or MRI

Developmentally abnormal with open or closed fontanel

MRI• Abnormal developmental/neurological exam with open or closed fontanel

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT or MRI

Developmentally abnormal with open or closed fontanel

MRI• Abnormal developmental/neurological exam with open or closed fontanel– MRI to evaluate brain parenchyma, extra-axial spaces

Macrocephaly

Non-communicating hydrocephalus

Macrocephaly

Anaplastic medulloblastoma

MacrocephalyClinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo)

Ultrasound

Developmentally normal with closed fontanel (>6 mo)

CT (or MRI)

Developmentally abnormal with open or closed fontanel

MRI• This approach to imaging macrocephaly reduces both unnecessary imaging and radiation exposure

References:Smith, MR, JC Leonidas, J Maytal. The Value of Head Ultrasound in Infants with Macrocephaly. Pediatric Radiology 1998; 28:143-146.Wilms G, Vanderschueren G, et al. CT and MR in infants with pericerebral collections and macrocephaly: benign enlargement of the subarachnoid spaces versus subdural collections. American Journal of Neuroradiology 1993; 14:855-860.Hudgins, R, Boydston WR. All Heads Great and Small, Macrocephaly. Children’s Healthcare of Atlanta. http://www.choa.org/default.aspx?id=921. Accessed June 15, 2008.

12-month-old male with macrocephaly and

developmental delay. What study is indicated?

A. B. C. D.

0% 0%0%0%

A. UltrasoundB. CTC. MRID. Brain PET scan

Imaging the Misshapen Head

• Common causes:– Macrocephaly– Microcephaly– Craniosynostosis– Posterior plagiocephaly

Imaging the Misshapen Head

• Common causes:– Macrocephaly– Microcephaly– Craniosynostosis– Posterior plagiocephaly

Microcephaly• Definition:

– Head circumference < 2SD (< 5%) below the mean for age, sex, race, and gestation

Microcephaly• Ddx:

– Congenital malformation

– Infection (TORCH)– Hypoxia-Ischemia – Old trauma– Toxic/Metabolic

Microcephaly• Clinical:

– Abnormal developmental or neurological exam

• Imaging:– MRI

Polymicrogyria

Imaging the Misshapen Head

• Common causes:– Macrocephaly– Microcephaly– Craniosynostosis– Posterior plagiocephaly

Imaging the Misshapen Head

• Common causes:– Macrocephaly– Microcephaly– Craniosynostosis– Posterior plagiocephaly

Craniosynostosis

• Definition:– Premature fusion of

cranial sutures• Synonyms:

– Craniostenosis, sutural synostosis, cranial dysostosis

• M:F = 3:1

Craniosynostosis

• Incidence: 3-5 cases per 10,000 live births– Sagittal – 56% (1/3600)

• Scaphocephaly

Craniosynostosis

• Incidence: 3-5 cases per 10,000 live births– Sagittal – 56% (1/3600)

• Scaphocephaly

Craniosynostosis

• Incidence: 3-5 cases per 10,000 live births– Sagittal – 56% (1/3600)

• Scaphocephaly– Coronal – 26% (1/7700)

• Brachycephaly

Craniosynostosis

• Incidence: 3-5 cases per 10,000 live births– Sagittal – 56% (1/3600)

• Scaphocephaly– Coronal – 26% (1/7700)

• Brachycephaly

Craniosynostosis

• Incidence: 3-5 cases per 10,000 live births– Sagittal – 56% (1/3600)

• Scaphocephaly– Coronal – 26% (1/7700)

• Brachycephaly– Metopic – 8% (1/25,000)

• Trigonocephaly

Craniosynostosis

• Incidence: 3-5 cases per 10,000 live births– Sagittal – 56% (1/3600)

• Scaphocephaly– Coronal – 26% (1/7700)

• Brachycephaly– Metopic – 8% (1/25,000)

• Trigonocephaly

Craniosynostosis

• Incidence: 3-5 cases per 10,000 live births– Sagittal – 56% (1/3600)

• Scaphocephaly– Coronal – 26% (1/7700)

• Brachycephaly– Metopic – 8% (1/25,000)

• Trigonocephaly– Lambdoid – 5% (1/40,000)

• Brachycephaly (bilateral) or Trapezoid skull (unilateral)

1

Craniosynostosis

• Incidence: 3-5 cases per 10,000 live births– Sagittal – 56% (1/3600)

• Scaphocephaly– Coronal – 26% (1/7700)

• Brachycephaly– Metopic – 8% (1/25,000)

• Trigonocephaly– Lambdoid – 5% (1/40,000)

• Brachycephaly (bilateral) or Trapezoid skull (unilateral)

– Other /syndromic – 5%

1

• Incidence: 3-5 cases per 10,000 live births– Sagittal – 56% (1/3600)

• Scaphocephaly– Coronal – 26% (1/7700)

• Brachycephaly– Metopic – 8% (1/25,000)

• Trigonocephaly– Lambdoid – 5% (1/40,000)

• Brachycephaly (bilateral) or Trapezoid skull (unilateral)

– Other /syndromic – 5%

1

Craniosynostosis

Posterior Plagiocephaly

• Posterior plagiocephaly:

Posterior Plagiocephaly

• Posterior plagiocephaly:– Synonyms:

• positional plagiocephaly, deformational plagiocephaly, positional molding, postural flattening

Posterior Plagiocephaly

• Posterior plagiocephaly:– Synonyms:

• positional plagiocephaly, deformational plagiocephaly, positional molding, postural flattening

– Commonly seen since “Back to Sleep” began in the 1990’s

Posterior Plagiocephaly

• Posterior plagiocephaly:– Synonyms:

• positional plagiocephaly, deformational plagiocephaly, positional molding, postural flattening

– Commonly seen since “Back to Sleep” began in the 1990’s– Asymmetrical flattening of the posterior skull due to

recumbent/sleep position

Posterior Plagiocephaly

• Posterior plagiocephaly:– Synonyms:

• positional plagiocephaly, deformational plagiocephaly, positional molding, postural flattening

– Commonly seen since “Back to Sleep” began in the 1990’s– Asymmetrical flattening of the posterior skull due to

recumbent/sleep position – Does not usually require imaging

Posterior Plagiocephaly

• Posterior plagiocephaly:– Synonyms:

• positional plagiocephaly, deformational plagiocephaly, positional molding, postural flattening

– Commonly seen since “Back to Sleep” began in the 1990’s– Asymmetrical flattening of the posterior skull due to

recumbent/sleep position – Does not usually require imaging– Must distinguish from lambdoid synostosis

Otherwise normal child with posterolateral flattening

Normal sutures/positional plagiocephalySagittal Lambdoid Coronal

Posterior Plagiocephaly

Otherwise normal child with posterolateral flattening

Posterior Plagiocephaly

NL

Normal sutures/ positional

plagiocephaly

CraniosynostosisLambdoid synostosis

Craniosynostosis

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull x-ray study

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

• When imaging is required, it depends on the risk category as determined by history/physical:

Craniosynostosis

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull x-ray study

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

• When imaging is required, it depends on the risk category as determined by history/physical:

CraniosynostosisRisk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull x-ray study

• Plain films:

CraniosynostosisRisk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull x-ray study

• Plain films: • Lowest radiation dose

CraniosynostosisRisk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull x-ray study

• Plain films: • Lowest radiation dose• Adequate screening for all craniosynostosis

Otherwise normal child with posterolateral flattening

Normal sutures/positional plagiocephalySagittal Lambdoid Coronal

Posterior Plagiocephaly

Craniosynostosis

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull x-ray study

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

Craniosynostosis

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull x-ray study

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

CraniosynostosisRisk Category ImagingIntermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

• Low-dose head CT:

CraniosynostosisRisk Category ImagingIntermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

• Low-dose head CT: • ~80% less radiation than standard head CT

CraniosynostosisRisk Category ImagingIntermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

• Low-dose head CT: • ~80% less radiation than standard head CT• Optimized for evaluation of the bones/sutures

Craniosynostosis – Intermediate Risk

Standard CT Low Dose CT

Standard CT Low Dose CT

Craniosynostosis – Intermediate Risk

Child with mild developmental delay and right

parieto-occiptal flattening

NLNormal sutures/ positional

plagiocephaly

Craniosynostosis – Intermediate Risk

Child with developmental delay and left posterior

flattening

Normal sutures/ posterior

plagiocephaly

Craniosynostosis – Intermediate Risk

NL

CraniosynostosisRisk Category ImagingIntermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

• Low-dose head CT: • ~80% less radiation than standard head CT• Optimized for evaluation of the bones/sutures• Only at CMH

Why you send patients here!

Low Radiation CT at CMH

• Dedicated low-dose pediatric protocols for:– Paranasal sinuses– Scoliosis spines– Cranial dermoid cysts– Facial bones– Cleft palate– Etc.

Craniosynostosis

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull x-ray study

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

Craniosynostosis

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull x-ray study

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

CraniosynostosisRisk Category ImagingHigh risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

• Standard head CT:

CraniosynostosisRisk Category ImagingHigh risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

• Standard head CT: • Higher radiation dose

CraniosynostosisRisk Category ImagingHigh risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

• Standard head CT: • Higher radiation dose

• Infants are significantly more affected by radiation (cancer risk)• Infants have a longer lifespan to manifest the effects (cancer risk)

CraniosynostosisRisk Category ImagingHigh risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

• Standard head CT: • Higher radiation dose

• Infants are significantly more affected by radiation (cancer risk)• Infants have a longer lifespan to manifest the effects (cancer risk)

• Use to evaluate skull and brain

CraniosynostosisRisk Category ImagingHigh risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

• Standard head CT: • Higher radiation dose

• Infants are significantly more affected by radiation (cancer risk)• Infants have a longer lifespan to manifest the effects (cancer risk)

• Use to evaluate skull and brain• Used by the surgeon for pre-surgical planning

• This is NOT a prerequisite for a plastic surgery consultation

CraniosynostosisRisk Category ImagingHigh risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

• Standard head CT: • Higher radiation dose

• Infants are significantly more affected by radiation (cancer risk)• Infants have a longer lifespan to manifest the effects (cancer risk)

• Use to evaluate skull and brain• Used by the surgeon for pre-surgical planning

• This is NOT a prerequisite for a plastic surgery consultation• Do not use as a screening exam for craniosynostosis

Craniosynostosis – High Risk

History: clinical exam suggesting coronal synostosis

NL

Craniosynostosis – High Risk

History: pre-operative coronal synostosis repair

Craniosynostosis – High Risk

History: pre-operative sagittal synostosis repair

Craniosynostosis – High Risk

History: pre-operative sagittal synostosis repair

3D Surface Rendering Max Intensity Projection Intracranial Superior View

Craniosynostosis – High Risk

History: pre-operative sagittal synostosis repair111111111111111111111111111111111111111111111111111111111111111111

Craniosynostosis – High Risk

History: pre-operative lambdoid synostosis repair

111111111111111111111111111111111111111111

NL

NL

CraniosynostosisRisk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull (plain films)

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

• This approach to imaging craniosynostosis and posterior plagiocephaly reduces both unnecessary imaging and radiation exposure

6-month-old infant with flat posterior skull & normal development. Which study is indicated?

A. B. C. D.

0% 0%0%0%

A. 3D CTB. MRIC. UltrasoundD. No imaging

Imaging the Misshapen Head

• Common causes:– Macrocephaly– Microcephaly– Craniosynostosis– Posterior plagiocephaly

Clinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo) UltrasoundDevelopmentally normal with closed fontanel (>6 mo) CT (or MRI)Developmentally abnormal with open or closed fontanel

MRI

How to Image Macrocephaly:

How to Image Craniosynostosis/Posterior Plagiocephaly:

Imaging the Misshapen Head

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull (plain films)

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

Clinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo) UltrasoundDevelopmentally normal with closed fontanel (>6 mo) CT (or MRI)Developmentally abnormal with open or closed fontanel

MRI

How to Image Macrocephaly:

How to Image Craniosynostosis/Posterior Plagiocephaly:

Imaging the Misshapen Head

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull (plain films)

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

Clinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo) UltrasoundDevelopmentally normal with closed fontanel (>6 mo) CT (or MRI)Developmentally abnormal with open or closed fontanel

MRI

How to Image Macrocephaly:

How to Image Craniosynostosis/Posterior Plagiocephaly:

Imaging the Misshapen Head

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull (plain films)

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

Clinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo) UltrasoundDevelopmentally normal with closed fontanel (>6 mo) CT (or MRI)Developmentally abnormal with open or closed fontanel

MRI

How to Image Macrocephaly:

• (

How to Image Craniosynostosis/Posterior Plagiocephaly:

Imaging the Misshapen Head

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull (plain films)

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformations

Clinical Presentation & Fontanel/Age ImagingDevelopmentally normal with open fontanel (<6 mo) UltrasoundDevelopmentally normal with closed fontanel (>6 mo) CT (or MRI)Developmentally abnormal with open or closed fontanel

MRI

How to Image Macrocephaly:

How to Image Craniosynostosis/Posterior Plagiocephaly:

Imaging the Misshapen Head

Risk Category ImagingLow risk – developmentally normal and posterior or posterolateral flattening only

No imaging, or 4-view skull (plain films)

Intermediate risk – children who don’t clearly fit into the low or high risk group

Low-dose head CT

High risk – developmentally abnormal and/or obvious head deformity almost certainly needing surgery

Standard head CT with 3D reformationsHow to Image Children in KC!

References1. Arch, Michael and Donald P. Frush. “Pediatric Body MDCT: A 5-year follow up survey of scanning

parameters used by Pediatric Radiologists.” AJR 2008; 191: 611-617.2. Brenner DJ, Hall EJ. Computed tomography: an increasing source of radiation exposure. N Engl J Med

2007; 357:2277-2284.3. Brenner, DJ Estimating cancer risks from pediatric CT: going from the qualitative to the quantitative.

Pediatric Radiology 2002: 32: 228-2314. Brenner DJ, Elliston CD, Hall EJ, and WE Berdon. Estimated risks of radiation-induced fatal cancer

from pediatric CT. AJR 2001;176: 289-296 5. Cohen, MM Jr. Epidemiology of Craniosynostosis. In: Cohen, MM Jr, ed Craniosynostosis:

diagnosis, evaluation, and management, 2nd ed. New York: Oxford University Press, 2000: 112-118.6. Goske MJ, et. al. The ‘Image Gently’ campaign: increasing CT radiation dose awareness through a

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Thanks/Contributed:

Julianne Dean, MDTiffany Lewis, DO

Lisa Lowe, MDTrent Phan, DO

Cindy Taylor, MD