- 1. Hemophilia A Inherited blood disease where your blood doesnt
clot normally.
2. Cause
- Hemophilia A (most common type)
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- Lack of clotting factor VIII
- Passed on with X chromosome
1 3. Symptoms
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- Joint pain and swelling - internal bleeding
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- Random bleeding or bruising
2 4. Symptoms
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- Sudden pain, swelling, and warmth of joints and muscles
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- Long and painful headaches
3 5. Characteristics
- Continuous bleeding after:
4 6. Characteristics
- More serious complications-
5 7. Characteristics
8. Who Is Affected?
-
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- Males have 50% chance of getting disease
-
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- Females have 50% chance of carrying disease
- Hemophilia is mostly in men
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- Men only have one X-chromosome
6 9. How It Normally Works Blood vessels are cut or damaged
Clotting factor recruits collagen
http://www.3dchem.com/molecules.asp?ID=195 8 7 Blood reacts to
clotting factors Platelets form plug at the injury site Bleeding
stops!! 11 10 9 How Disease Affects Homeostasis No clotting factor
to recruit collagen No clotting factor for blood to react to
Platelets dont form a plug Bleeding Does Not Stop! 12 10.
Diagnosis
- Family history of hemophilia
- Blood testing from a child or adult
13 11. Treatment
- Replacement of the missing clotting factor
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- Can be given as nasal medication
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- Helps body release factor VIII
14 12. Prevention
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- Figures out the chance of your child getting hemophilia
15 13. Bibliography - Contents
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http://www.nhlbi.nih.gov/health/dci/Diseases/hemophilia/hemophilia_what.html
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http://www.mayoclinic.com/health/hemophilia/DS00218/DSECTION=causes
- http://ghr.nlm.nih.gov/condition/hemophilia
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http://www.mayoclinic.com/health/hemophilia/DS00218/DSECTION=symptoms
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http://www.inheritedhealth.com/condition/Hemophilia/179#symptomsandcharacteristics
- http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001565/
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http://www.mayoclinic.com/health/hemophilia/DS00218/DSECTION=treatments-and-drugs
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http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/Clotting.html
14. Bibliography - Pictures
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1-http://biomed.brown.edu/Courses/BI108/2006-108websites/group01Heparin-coatedOxygenators/pages/Heparin_pharmacokinetics.htm
- 2
-http://en.nkfu.com/what-is-hemophilia-signs-and-treatment/
- 3 -http://www.tmj.ro/article.php?art=58506380129851
- 4 -http://www.unm.edu/~mpachman/Blood/displaz.htm
- 5
-http://www.psd202.org/PEHS/departments/science/tmurphy/sixth_hour_web/Hemophilia/symptons_and_characteristics.html
- 6
-http://presscoverage.us/soapbox/the-redefinition-of-perfect/
- 7 -http://www.health911.com/cuts-&-wounds
- 8 -http://www.3dchem.com/molecules.asp?ID=195
- 9
-http://www.healthjockey.com/2008/02/11/vacuming-blood-clots-proves-to-be-effective-heart-attack-treatment/
- 10
-http://sciencephoto.com/images/download_lo_res.html?id=802600116
- 11 -http://www.fotosearch.com/illustration/blood-drop.html
- 12 -http://www.flickr.com/photos/csessums/4966652884/
- 13
-http://www.thereforyou.com/about-hemophilia/overview/who-gets-hemophilia.html
- 14
-http://products.hospira.com/search/productDetails?listNumber=DESMOPRESSIN_ACETATE&page=Drugs&sort=ndc&order=asc
- 15
-http://www.thereforyou.com/about-hemophilia/gist-of-genetics/genetics-counseling.html