Got Tissue?Got Tissue?How Arizona Created a Statewide How Arizona Created a Statewide Virtual Tissue BankVirtual Tissue Bank

Jim MatthewsArizona Biomedical Research Commission

Jungdae Kokotov5AM Solutions

July 27, 2010 www.5amsolutions.com

Webinar Technical DetailsWebinar Technical Details

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The Issue of TissueThe Issue of Tissue

Biospecimens are at the core of discovery-oriented scientific research.

Issues:Collecting

Annotating

Finding

Obtaining

About ABRCAbout ABRC

What Led Us HereWhat Led Us Here

Our ProcessOur Process

The Solicitation

Our VisionOur Vision

Sun Health Research Institute

Arizona Biospecimen ConsortiumArizona Biospecimen Consortium

A Consortium of Institutional Partners

Our ChallengesOur Challenges

Partnership buy-in

Synchronicity of technology + governance

From Vision to Working SystemFrom Vision to Working System

Agile processes

Engaged stakeholders

5AM participation in Consortium meetings

Biolocator: High Level WorkflowBiolocator: High Level Workflow

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How We Integrate – and Share – the DataHow We Integrate – and Share – the Data

ABLABL

Commercial BioBanking

Solution

Commercial BioBanking

Solution

Custom Application

Custom Application

CBM – NCI’s caGrid

CBM – NCI’s caGrid

Automatic data pull Periodic data import

Share Information Over NCI’s caGridShare Information Over NCI’s caGrid

http://portal.training.cagrid.org/web/guest/home

Our Technical ChallengesOur Technical Challenges

Mapping dataFields

Diverse systems, diverse data fields How do we find a common model…? NCI’s Common Biorepository Model

Values Diverse systems, diverse data values How do we find a common disease vocabulary…? SNOMED-CT

Collection DateQuality RatingSpecimen TypeTumor RatingDisease TypeLiquid NitrogenParaffin Block

Collection DateQuality RatingSpecimen TypeTumor RatingDisease TypeLiquid NitrogenParaffin Block

DateTimeTissue TypeCancer BooleanLab Report Freetext

DateTimeTissue TypeCancer BooleanLab Report Freetext

Malignant Tumor of BreastMalignant Tumor of Breast

Breast CarcinomaBreast Carcinoma

254837009254837009Breast CancerBreast CancerBreast Cancer Type 1 Susceptibility ProteinBreast Cancer Type 1 Susceptibility Protein

https://demo.5amsolutions.com/tissuelocator-web/https://demo.5amsolutions.com/tissuelocator-web/

ABRC’s Future Role in the Arizona Biomedical ConsortiumABRC’s Future Role in the Arizona Biomedical Consortium

Funding the ABL program

Demonstrating usefulness

Assisting institutional partnersEquipment

Personnel

Integration Support

Next Steps for the Arizona Biospecimen ConsortiumNext Steps for the Arizona Biospecimen Consortium

Develop a Platform for Future ServicesCord blood bank

Cord blood patient registry

Trauma center data warehouse linkage

Expand our Partners + ParticipantsPhoenix Indian Medical Center

Phoenix VA

Others

Contact UsContact Us

James MatthewsDeputy Director

Arizona Biomedical Resource Commission

james.matthews@azabrc.gov

Jungdae KokotovProject ManagerBiolocator

5AM Solutions

jkokotov@5amsolutions.com

Arizona Biospecimen Locator Demo:https://demo.5amsolutions.com/tissuelocator-web/

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