Genes and Their Evolution: Population Genetics

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Transcript of Genes and Their Evolution: Population Genetics

Chapter 4 Genes and Their Evolution:

Population Genetics

Demes, Reproductive Isolation, and species

What is a population?

– Fluid concept

–Groups beneath species level?

• Deme (local breeding population)

• Subspecies, (Race)

• Gene pool

Demes, Reproductive Isolation, and species

• Reproductive isolation

–Microevolution

–Macroevolution

Figure 4.3a

Microevolution

Macroevolution

Figure 4.3b

Mutation: The only source of New Allelles • Point mutations • Transposable elements • Klinefelter’s syndrome • Nonsynonymous point mutation • Induced mutations • mutagens

Natural Selection: Advantageous characteristics, survival and

reproduction

• Fitness

• Directional Selection

• Stabilizing selection

• Disruptive selection

Figure 4.9

Industrial Melanism

Melanic/Nonmelanic

Natural Selection in Humans: Abnormal hemoglobins and resistance to malaria

• Positive selection

• Hemolytic anemias

• Hemoglobinopathies

• Ballanced polymorphism

• Capillaries

Genetic Drift: Genetic Change due to chance

• Founder effect and genetic bottleneck

• More important with small populations

• exogamous

Gene flow: Spread of genes across population Boundaries

• Admixture Tends to make populations genetically similar, offset problems of inbreeding