General Structure of Ion Channels

Satadru DeM.Phil 1st year

Voltage gated ion channels:• Na+ channel• K+ channels• Ca2+ channel• Cl- channel

Ligand gated ion channels:• Nicotinic Ach-R• GABAA –R• Glycine – R• Ionotropic Glutamate – R• Purinoceptor P2X

Voltage Gated Sodium Channel

Voltage Gated Calcium Channel

Voltage Gated Potassium Channels

KA / Fast or Early

KV / Delayed Rectifier

KS / Serotonin dependant

KCa / Calcium dependant

Kir / Inward rectifying

KATP / ATP dependant

Kach / GIRK-1

K leak channels

Chloride Channel (ClC)Chloride-nucleotide Channel (Cln)Phospholemman

Voltage Gated Chloride Channel

Ligand Gated Ion channels

Nicotinic Ach Receptor GABAA Receptor

Glycine Receptor

Ionotropic Glutamate Receptor

NMDA-Receptor

Purinoceptor – P2X

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