Post on 19-Dec-2015
Evidence-based Medicine as a Patient Safety Evidence-based Medicine as a Patient Safety ToolToolKey Concepts, Emerging ApplicationsKey Concepts, Emerging Applications
Evidence-based Medicine as a Patient Safety Evidence-based Medicine as a Patient Safety ToolToolKey Concepts, Emerging ApplicationsKey Concepts, Emerging Applications
The Quality Colloquium at Harvard UniversityBoston, Massachusetts
Paul H. Keckley, Ph.D.Vanderbilt Medical Center
August 20, 2006
The Quality Colloquium at Harvard UniversityBoston, Massachusetts
Paul H. Keckley, Ph.D.Vanderbilt Medical Center
August 20, 2006
What we’ll coverWhat we’ll coverWhat we’ll coverWhat we’ll cover
The momentum for safety EBM as a means to an end Implications for provider organizations
BIOTECHBIOTECH
INNOVATORSINNOVATORS
ADMINISTRATORS/WATCHDOGSADMINISTRATORS/WATCHDOGS
SERVICE PROVIDERSSERVICE PROVIDERS
PhysiciansPhysicians
HCITHCIT
PharmaPharma
DeviceDevice
HospitalsHospitalsOutpatientFacilities
OutpatientFacilities
InsurersInsurers
RegulatorsRegulators
Long TermCare
Long TermCare
BioTechBioTech
Professional Societies/
Special Interests
Professional Societies/
Special Interests
Accrediting Agencies
Accrediting Agencies
DiseaseManagement
DiseaseManagement
EmployersEmployers
CAMCAM
MediaMedia
AcademicMedicine
AcademicMedicine
CONSUMERSCONSUMERS
Allied HealthProfessionalsAllied HealthProfessionals
$1.9 Trillion
$1.3 Trillion
$696 Billion
$246 Billion
0.0
0.5
1.0
1.5
2.0
1980 1990 2000 2005(Projected)
$ T
rilli
ons
8.8% GDP8.8% GDP
12.0% GDP
12.0% GDP
13.3%GDP
13.3%GDP
15.7%GDP
(projected)
15.7%GDP
(projected)
$6320 per person in the U.S.!$6320 per person in the U.S.!$6320 per person in the U.S.!$6320 per person in the U.S.!
““The quality of care we get is far from the care The quality of care we get is far from the care we should be getting” we should be getting” — Don Berwick, IHI— Don Berwick, IHI““The quality of care we get is far from the care The quality of care we get is far from the care we should be getting” we should be getting” — Don Berwick, IHI— Don Berwick, IHI
Preventive care deficiencies•Child immunizations 76%•Influenza vaccine 52%•Pap smear 82%
Preventive care deficiencies•Child immunizations 76%•Influenza vaccine 52%•Pap smear 82%
Acute care deficiencies•Antibiotic misuse 30-70%•Prenatal care 74%
Acute care deficiencies•Antibiotic misuse 30-70%•Prenatal care 74%
Chronic care deficiencies•Beta blockers 50%•Diabetes eye exam 53%
Chronic care deficiencies•Beta blockers 50%•Diabetes eye exam 53%
Hospital care deficiencies•Proper CHF care 50%•Preventable deaths 14%•Preventable ADEs 1.8/100 admits Life threatening 20% Serious 43%
Hospital care deficiencies•Proper CHF care 50%•Preventable deaths 14%•Preventable ADEs 1.8/100 admits Life threatening 20% Serious 43%
““Quality of Care”Quality of Care”Safe
EffectivePatient-centered
TimelyEfficient
Equitable
““Quality of Care”Quality of Care”Safe
EffectivePatient-centered
TimelyEfficient
Equitable
Surgery care deficiencies•Inappropriate hysterectomy 16%•Inappropriate CABG surgeries 14%
Surgery care deficiencies•Inappropriate hysterectomy 16%•Inappropriate CABG surgeries 14%
What the evidence says is what you get What the evidence says is what you get
(half the time)(half the time)
What the evidence says is what you get What the evidence says is what you get
(half the time)(half the time)
Condition% Recommended Care
Received
Senile Cataract 78.7
Breast cancer 75.7
Prenatal Care 73.0
Low back pain 68.5
Coronary artery disease
68.0
Hypertension 64.7
Congestive heart failure
63.9
Cerebrovascular disease
59.1
Chronic obstructive pulmonary disease
58.0
Depression 57.7
Orthopedic conditions 57.2
Osteoarthritis 57.3
Colorectal cancer 53.9
Condition% Recommended Care
Received
Asthma 53.5
Benign prostatic hyperplasia
53.0
Hyperlipidemia 48.6
Diabetes mellitus 45.4
Headache 45.2
Urinary tract infection 40.7
Community acquired pneumonia
39.0
Sexually transmitted diseases
36.7
Dyspepsia/peptic ulcer disease
32.7
Atrial fibrillation 24.7
Hip fracture 22.7
Alcohol dependence 10.5
McGlynn et al “The Quality of Health Care Delivered to Adults in the United States” NEJM June 26, 2003McGlynn et al “The Quality of Health Care Delivered to Adults in the United States” NEJM June 26, 2003McGlynn et al “The Quality of Health Care Delivered to Adults in the United States” NEJM June 26, 2003McGlynn et al “The Quality of Health Care Delivered to Adults in the United States” NEJM June 26, 2003
First
Third
FourthSource: S.F. Jencks, E.D. Huff, and T. Cuerdon, “Change in the Quality of Care Delivered to Medicare Beneficiaries, 1998–1999 to 2000–2001,” Journal of the American Medical Association 289, no. 3 (Jan. 15, 2003): 305–312.
Second
WA
OR
ID
MT ND
WY
NV
CAUT
AZ NM
KS
NE
MN
MO
WI
TX
IA
ILIN
AR
LA
AL
SC
TNNC
KY
FL
VA
OH
MI
WV
PA
NY
AK
MD
MEVT
NH
MA
RI
CT
DE
DCCO
GAMS
OK
NJ
SD
Quartile Rank
Note: State ranking based on 22 Medicare performance measures.Note: State ranking based on 22 Medicare performance measures.
Quality depends on where you liveQuality depends on where you liveQuality depends on where you liveQuality depends on where you live
Errors aboundErrors aboundErrors aboundErrors abound
1. Adverse drug events (ADEs, ADRs)2. Iatrogenic infections
• Post-operative deep wound infections• Urinary tract infections (UTI)• Lower respiratory infections (pneumonia or bronchitis)• Bacteremias and septicemias
3. Decubitus ulcers4. Mechanical device failures5. Complications of central and peripheral venous lines6. Deep venous thrombosis (DVT) / pulmonary embolism (PE)7. Strength, agility and cognition8. Blood product transfusion9. Patient transitions
1. Adverse drug events (ADEs, ADRs)2. Iatrogenic infections
• Post-operative deep wound infections• Urinary tract infections (UTI)• Lower respiratory infections (pneumonia or bronchitis)• Bacteremias and septicemias
3. Decubitus ulcers4. Mechanical device failures5. Complications of central and peripheral venous lines6. Deep venous thrombosis (DVT) / pulmonary embolism (PE)7. Strength, agility and cognition8. Blood product transfusion9. Patient transitions
80% of ADE’s avoidable80% of ADE’s avoidable80% of ADE’s avoidable80% of ADE’s avoidable
Class % Description Avoidable?
Pharm
Expected28.0 Know drug reactions Yes
Physio
Renal23.0
Failure to adjust for decreased
Renal functionYes
Physio
Age14.2 Failure to adjust for patient age Yes
Physio
Weight5.7
Failure to adjust for patient body mass
Yes
Order
Dosage5.0 Error in dosage on order Yes
Physio
Hernal4.6
Failure to adjust for known hematologic
Yes
Total
preventable80.3
Study: Health Care Costs, Error Rates Higher in Study: Health Care Costs, Error Rates Higher in U.S. Than in Other CountriesU.S. Than in Other CountriesStudy: Health Care Costs, Error Rates Higher in Study: Health Care Costs, Error Rates Higher in U.S. Than in Other CountriesU.S. Than in Other Countries
November 04, 2005
For the report, researchers surveyed 6,957 adults between March and June 2005 who recently had been hospitalized, had surgery or reported health problems in the U.S., Australia, Canada, Britain, New Zealand and Germany. The survey, which is the largest to examine health care in several nations during the same time period, found that U.S. residents were more likely than patients in other nations to forego medical care because of costs. In addition, U.S. respondents reported the easiest access to specialists but the most difficulty getting care during nights and weekends (Washington Post, 11/4). Patients from all six countries reported medical errors, uncoordinated care and poor management of chronic diseases (CQ HealthBeat, 11/3).
The study also found the following:
34% of U.S. patients surveyed reported getting the wrong medication or dose, incorrect test results, a mistake in their treatment or late notification of abnormal test results, compared with 30% of Canadians, 27% of Australians, 25% of New Zealanders, 23% of Germans and 22% of Britons;
About half of U.S. residents reported that they had decided not to fill a prescription, see a physician when sick or have recommended follow-up tests because of costs, compared with 38% of patients in New Zealand, 34% in Australia, 28% in Germany, 26% in Canada and 13% in Britain;
Nearly one-third of U.S. patients reported paying more than $1,000 in out-of-pocket medical expenses in the past year, compared with 14% of Canadian and Australian patients and a much lower proportion of patients in the other countries (Washington Post, 11/4);
7% of U.S. residents who had been hospitalized in the past two years reported developing an infection while in the hospital, compared with 10% of Britons and 3% of Germans
November 04, 2005
For the report, researchers surveyed 6,957 adults between March and June 2005 who recently had been hospitalized, had surgery or reported health problems in the U.S., Australia, Canada, Britain, New Zealand and Germany. The survey, which is the largest to examine health care in several nations during the same time period, found that U.S. residents were more likely than patients in other nations to forego medical care because of costs. In addition, U.S. respondents reported the easiest access to specialists but the most difficulty getting care during nights and weekends (Washington Post, 11/4). Patients from all six countries reported medical errors, uncoordinated care and poor management of chronic diseases (CQ HealthBeat, 11/3).
The study also found the following:
34% of U.S. patients surveyed reported getting the wrong medication or dose, incorrect test results, a mistake in their treatment or late notification of abnormal test results, compared with 30% of Canadians, 27% of Australians, 25% of New Zealanders, 23% of Germans and 22% of Britons;
About half of U.S. residents reported that they had decided not to fill a prescription, see a physician when sick or have recommended follow-up tests because of costs, compared with 38% of patients in New Zealand, 34% in Australia, 28% in Germany, 26% in Canada and 13% in Britain;
Nearly one-third of U.S. patients reported paying more than $1,000 in out-of-pocket medical expenses in the past year, compared with 14% of Canadian and Australian patients and a much lower proportion of patients in the other countries (Washington Post, 11/4);
7% of U.S. residents who had been hospitalized in the past two years reported developing an infection while in the hospital, compared with 10% of Britons and 3% of Germans
Lack of capital and resources
Lack of capital and resources
Explosion in clinical knowledge
Explosion in clinical knowledge
Lack of political will, leadership
Lack of political will, leadership
Lack of consumer
involvement
Lack of consumer
involvement
Lack of appropriate technology
Lack of appropriate technology
Lack of trust among Key
Players
Lack of trust among Key
Players
Lack of incentives for
right behaviors
Lack of incentives for
right behaviors
Runaway Costs
Runaway Costs
Lack of Access
Lack of Access
InconsistentQuality
InconsistentQuality
The system is in meltdown..The system is in meltdown..The system is in meltdown..The system is in meltdown..
““Quality” is our number one concern!!Quality” is our number one concern!!““Quality” is our number one concern!!Quality” is our number one concern!!
Evidence Based Care
Patient Centered Approach
System Orientation
Evidence Based Care
Patient Centered Approach
System Orientation
To most, quality means safe, accessible To most, quality means safe, accessible carecareTo most, quality means safe, accessible To most, quality means safe, accessible carecare
Clinical ProcessesClinical Processes
•Adherence to evidence-based pathways in the diagnosis and intervention planning with patients
•Safe, effective, timely, patient-centered care•Collaborative care management
Clinical ProcessesClinical Processes
•Adherence to evidence-based pathways in the diagnosis and intervention planning with patients
•Safe, effective, timely, patient-centered care•Collaborative care management
Structural ProcessesStructural Processes
•Access to needed services in appropriate settings•Paperwork/administrative procedures to access services
and document transactions
Structural ProcessesStructural Processes
•Access to needed services in appropriate settings•Paperwork/administrative procedures to access services
and document transactions
Service Delivery ProcessesService Delivery Processes
•Satisfaction with care management processes•Amenities to reduce anxiety, increase comfort
Service Delivery ProcessesService Delivery Processes
•Satisfaction with care management processes•Amenities to reduce anxiety, increase comfort
Clinical
Excellence!
Clinical
Excellence!
SupportiveSupportive
PrimaryPrimary
Patient (consumer)preferences, beliefs
and values
Patient (consumer)preferences, beliefs
and values
Evidence-based medicine is not understoodEvidence-based medicine is not understoodEvidence-based medicine is not understoodEvidence-based medicine is not understood
“Evidence-based medicine is the judicious application of relevant scientific studies to patient preferences and values.”
“Evidence-based medicine is the judicious application of relevant scientific studies to patient preferences and values.”
Judiciousintegration
of relevant science
Judiciousintegration
of relevant science
Clinician trainingClinician trainingand experienceand experience
Clinician trainingClinician trainingand experienceand experience
Guidelines: Guidelines: The Framework for Evidence-based MedicineThe Framework for Evidence-based MedicineGuidelines: Guidelines: The Framework for Evidence-based MedicineThe Framework for Evidence-based Medicine
“Systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances”
– IOM ’92
Derived from… 20,000 RCTs annually 4,000 guidelines since 1989 2,500 periodicals in NLS
Every guideline is not evidence-based, and someguidelines are about who, what should be done
Derived from… 20,000 RCTs annually 4,000 guidelines since 1989 2,500 periodicals in NLS
Every guideline is not evidence-based, and someguidelines are about who, what should be done
PICO: the framework for guidelines…PICO: the framework for guidelines…
P… what’s the population?I…what intervention am I testing?C… compared to what other intervention?O… what outcome is being tested?
P… what’s the population?I…what intervention am I testing?C… compared to what other intervention?O… what outcome is being tested?
Then evidence-linked algorithms form the Then evidence-linked algorithms form the framework for guidelinesframework for guidelinesThen evidence-linked algorithms form the Then evidence-linked algorithms form the framework for guidelinesframework for guidelines
Studies are graded using various schemes..Studies are graded using various schemes..
In practice, tools are used to stay abreast..In practice, tools are used to stay abreast..
Systematic ReviewsCochrane LibrarySystematic ReviewsCochrane Library
Clinical EvidencePOEMsClinical EvidencePOEMs
Valu
e
Medline, PubMedMedline, PubMed
EBM Practice GuidelineEBM Practice Guideline
CATs, Best Evidence,ACP Journal ClubCATs, Best Evidence,ACP Journal Club
Reviews: Up-to-Date, 5-Min Clinical Consult
Reviews: Up-to-Date, 5-Min Clinical Consult
Better care is the result; it is also a more Better care is the result; it is also a more efficient way to operate a clinical enterpriseefficient way to operate a clinical enterpriseBetter care is the result; it is also a more Better care is the result; it is also a more efficient way to operate a clinical enterpriseefficient way to operate a clinical enterprise
Outcomes (p<0.0001)
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
Death RespiratoryFailure
ProlongedLength of Stay
Elevated TotalCharges
Blood Cultures AppropriateAntibiotics
Pathway non Pathway Ann. Epidemiology 2004:14:669-675
And then we draw conclusions: what do we learn And then we draw conclusions: what do we learn by examining the evidence?by examining the evidence?And then we draw conclusions: what do we learn And then we draw conclusions: what do we learn by examining the evidence?by examining the evidence?
Observational Study (n=1): why women live longer than men!”Observational Study (n=1): why women live longer than men!”
The data correlates adherence to evidence-based practice with…The data correlates adherence to evidence-based practice with…
Improved outcomes Reduced variation Improved patient adherence Improved efficiency Reduced errors
So why isn’t evidence-based practice more consistently provided?
Improved outcomes Reduced variation Improved patient adherence Improved efficiency Reduced errors
So why isn’t evidence-based practice more consistently provided?
Challenge: Knowledge ExplosionChallenge: Knowledge Explosion
20,000 biomedical journals >150,000 medical articles
published each month >300,000 randomized controlled
trials
““We are drowning in We are drowning in information but starved information but starved for knowledge.”—Naisbitt, ‘82for knowledge.”—Naisbitt, ‘82
Challenge: Lack of EvidenceChallenge: Lack of Evidence
How many questions have any evidence? (BMJ 2000)
0 50 100 150 200 250 300 350 400
Uncertain 375Uncertain 375
Partial Answer 299Partial Answer 299
Answered 358Answered 358Beneficial ……………………..
248Ineffective or harmful ………..
43Trade-off ………………………
67
Likely to be beneficial ………. 235
Unlikely to be beneficial ……. 64
Unknown effectiveness …….. 375 Number of Interventions
Challenge: Source CredibilityChallenge: Source Credibility
Shaneyfelt et al: (JAMA, 1999)Of 279 guidelines developed by medical societies, most do not adhere to IOM standards for methodological review (evidence-grading)
Grilli et al: (Lancet, 2000)431 guidelines reviewed; 82% lack evidence-grading review assessment
Shaneyfelt et al: (JAMA, 1999)Of 279 guidelines developed by medical societies, most do not adhere to IOM standards for methodological review (evidence-grading)
Grilli et al: (Lancet, 2000)431 guidelines reviewed; 82% lack evidence-grading review assessment
Challenge: ReliabilityChallenge: Reliability
YOU ARE
HERE
Challenge : TimelinessChallenge : TimelinessChallenge : TimelinessChallenge : TimelinessThe solid line represents the Kaplan-
Meier curve for the Agency for Healthcare Research and Quality (AHRQ)
guidelines.
Dashed lines represent the 95% confidence
interval (JAMA. 2001;286:1461-1467)
◙–
Challenge: Commercial InterestsChallenge: Commercial InterestsChallenge: Commercial InterestsChallenge: Commercial Interests
1. Digital imaging2. Drug-coated stents3. Oral cancer treatments4. Minimally invasive surgery5. Sepsis treatment6. Implantable devices7. Microscopic cameras8. Diabetes devices9. At-home health test kits10. Embryonic stem cell research
$$$$
Challenge: Media AttentionChallenge: Media Attention
Challenge: Physician TrainingChallenge: Physician Training
Provide patient centered care
Work in interdisciplinary teams
Employ evidence-based practice
Apply quality improvement
Utilize informatics
Health Professions Education: A Bridge to Quality
Institute of Medicine 2003
73% of patients depend on physicians to make decisions for them!73% of patients depend on physicians to make decisions for them!
“INFORMED” PARENTAL
“INFORMED” PARENTAL
INTERMEDIATE SHARED DECISION MAKING
INTERMEDIATE SHARED DECISION MAKING
PATIENT AS DECISION-MAKER
PATIENT AS DECISION-MAKER
4.8%Stronglydisagree
4.8%Stronglydisagree
*Adapted from Guyatt et al. Incorporating Patient Values in: Guyatt et al. Users’ Guide to the Medical Literature:
Essentials of Evidence –based Clinical Practice. JAMA 2001
**Arora NK and McHorney CA. Med Care. 2000; 38:335
17.1% Strongly
Agree
17.1% Strongly
Agree
45%Agree45%
Agree11%11% 22.5%
Disagree22.5%
Disagree
Challenge: Consumer ExpectationsChallenge: Consumer Expectations
Lots of explanations and excuses…Lots of explanations and excuses…Lots of explanations and excuses…Lots of explanations and excuses…
“they don’t pay for it..” “the tools aren’t available” “my patients don’t care” “it’s a fad” “the only evidence I need is what I know”
So what does this have to do with So what does this have to do with safety?safety?
EBM, quality and safety are closely EBM, quality and safety are closely related…related…EBM, quality and safety are closely EBM, quality and safety are closely related…related…
Clinical ProcessesClinical Processes
•Adherence to evidence-based pathways in the diagnosis and intervention planning with patients
•Safe, effective, timely, patient-centered care•Collaborative care management
Clinical ProcessesClinical Processes
•Adherence to evidence-based pathways in the diagnosis and intervention planning with patients
•Safe, effective, timely, patient-centered care•Collaborative care management
Structural ProcessesStructural Processes
•Access to needed services in appropriate settings•Paperwork/administrative procedures to access
services and document transactions
Structural ProcessesStructural Processes
•Access to needed services in appropriate settings•Paperwork/administrative procedures to access
services and document transactions
Service Delivery ProcessesService Delivery Processes
•Satisfaction with care management processes•Amenities to reduce anxiety, increase comfort
Service Delivery ProcessesService Delivery Processes
•Satisfaction with care management processes•Amenities to reduce anxiety, increase comfort
Clinical
Excellence!
Clinical
Excellence!
SupportiveSupportive
PrimaryPrimary
QualityQualityImprovementImprovement
““Do things well”Do things well”
““It’s cookbook It’s cookbook Medicine”Medicine”
““we don’t have we don’t have the tools”the tools”
““we never didwe never didit that way before”it that way before”
SafetySafety““Do no harm”Do no harm”
Clinical ExcellenceClinical Excellence““Do right things well”Do right things well”
The application of EBM to safety is foundationalThe application of EBM to safety is foundational
Safe, evidence-based careSafe, evidence-based careSafe, evidence-based careSafe, evidence-based care
Clinical ProcessesClinical Processes•EffectiveEffective
•Patient CenteredPatient Centered
Clinical ProcessesClinical Processes•EffectiveEffective
•Patient CenteredPatient Centered
Structural ProcessesStructural Processes•Equitable•Accessible
Structural ProcessesStructural Processes•Equitable•Accessible
Service Delivery ProcessesService Delivery Processes
•Timeliness, Efficient•Equitable
Service Delivery ProcessesService Delivery Processes
•Timeliness, Efficient•Equitable
Clinical
Excellence!
Clinical
Excellence!
SupportiveSupportive
PrimaryPrimary
Admissions ManagementAdmissions ManagementEvaluating appropriately, directing Evaluating appropriately, directing
resources effectivelyresources effectively
Admissions ManagementAdmissions ManagementEvaluating appropriately, directing Evaluating appropriately, directing
resources effectivelyresources effectively
Care Team ManagementCare Team ManagementRecruiting, equipping and Recruiting, equipping and
holding accountable care teamsholding accountable care teams
Care Team ManagementCare Team ManagementRecruiting, equipping and Recruiting, equipping and
holding accountable care teamsholding accountable care teams
Pathway ManagementPathway ManagementBuilding and updating pathways, Building and updating pathways,
order sets and guidelines for care teamsorder sets and guidelines for care teams
Pathway ManagementPathway ManagementBuilding and updating pathways, Building and updating pathways,
order sets and guidelines for care teamsorder sets and guidelines for care teams
Outcome ManagementOutcome Management Measuring what works best and whyMeasuring what works best and why
Outcome ManagementOutcome Management Measuring what works best and whyMeasuring what works best and why
Risk ManagementRisk ManagementAvoiding error, conducting Avoiding error, conducting
root cause analysisroot cause analysis
Risk ManagementRisk ManagementAvoiding error, conducting Avoiding error, conducting
root cause analysisroot cause analysis
Discharge ManagementDischarge ManagementTeaching, equipping patients for Teaching, equipping patients for
guided self-care, follow-upguided self-care, follow-up
Discharge ManagementDischarge ManagementTeaching, equipping patients for Teaching, equipping patients for
guided self-care, follow-upguided self-care, follow-up
For a provider organization, there are six key For a provider organization, there are six key operational applications where EBM is central…operational applications where EBM is central…For a provider organization, there are six key For a provider organization, there are six key operational applications where EBM is central…operational applications where EBM is central…
Physician leadership is essential!Physician leadership is essential!
Point of care decision-support tools are essentialPoint of care decision-support tools are essentialPoint of care decision-support tools are essentialPoint of care decision-support tools are essential
0 50 100 150 200 250 300
Clinical Information
ComputerizedPhysician Order Entry
Decision Support
Electronic MedicalRecord
Medical Management
HCIT: Where do we start selecting companies?HCIT: Where do we start selecting companies?Numbers of companies currently supporting these applicationsNumbers of companies currently supporting these applicationsHCIT: Where do we start selecting companies?HCIT: Where do we start selecting companies?Numbers of companies currently supporting these applicationsNumbers of companies currently supporting these applications
Source: 2005 Healthcare Informatics, Resource GuideSource: 2005 Healthcare Informatics, Resource Guide
129129
259259
197197
165165
246246
The cat is out of the bag!!The cat is out of the bag!!The cat is out of the bag!!The cat is out of the bag!!
SummarySummary
EBM is a journey to clinical excellence: it’s about safety, quality improvement and evidence-based care
Applying EBM to error avoidance is fundamental: it leverages research about efficacy and effectiveness
To deliver safe evidence-based care, an organization must invest in processes and information technologies to support leaders in the journey
Our results will be public.
EBM is a journey to clinical excellence: it’s about safety, quality improvement and evidence-based care
Applying EBM to error avoidance is fundamental: it leverages research about efficacy and effectiveness
To deliver safe evidence-based care, an organization must invest in processes and information technologies to support leaders in the journey
Our results will be public.
ContactContactContactContact
Paul H. Keckley, Ph.D.Paul H. Keckley, Ph.D.Executive DirectorExecutive DirectorVanderbilt Center for Evidence-based MedicineVanderbilt Center for Evidence-based MedicineAssociate ProfessorAssociate ProfessorVanderbilt University School of MedicineVanderbilt University School of MedicineD-3300 Medical Center NorthD-3300 Medical Center NorthNashville, TN 37232-2104Nashville, TN 37232-2104paul.keckley@vanderbilt.edupaul.keckley@vanderbilt.edu615-343-3922615-343-3922www.ebm.vanderbilt.eduwww.ebm.vanderbilt.edu