Prof. Fausto J. Pinto, FESC, FACCHead, Cardiology Dpt/University Hospital Sta Maria-HPV

University of Lisbon, Portugal

Professor Fausto J. Pinto, MD, PhD, FESC, FASE, FACC, FSCAI

•• DisclosuresDisclosures: :

President, European Society of Cardiology (ESC)President, European Society of Cardiology (ESC)

ConsultancyConsultancy, advisory boards and , advisory boards and modestmodestlecture fees: lecture fees:

Abbott, Astra Zeneca, Bayer, Bial, BMS, Benecke, Abbott, Astra Zeneca, Bayer, Bial, BMS, Benecke, Biotronik, Boehringher Ingelheim, Biotronik, Boehringher Ingelheim, Boston Boston Scientific, CovidienScientific, Covidien, GE, Irokio, Medtronic, , GE, Irokio, Medtronic, Menarini, Merck, MSD, Novartis, Pfizer, Sanofi, Menarini, Merck, MSD, Novartis, Pfizer, Sanofi, Servier, St Jude Medical, TabukServier, St Jude Medical, Tabuk

Joyce E et al EJHF 2015

LV Strain Curves according to the Primary Endpoint

Joyce E et al EJHF 2015

Event Free survival according to LV GLS

Joyce E et al EJHF 2015

Study design.

Negishi K et al. Eur Heart J Cardiovasc Imaging 2014;15:324-331

Trends of EF in three different chemo regimens, with or without beta-blocker.

Negishi K et al. Eur Heart J Cardiovasc Imaging 2014;15:324-331

Trends of GLS in three different chemo regimens, with or without beta-blocker.

Negishi K et al. Eur Heart J Cardiovasc Imaging 2014;15:324-331

Representative cases with and without beta-blocker therapy.

Negishi K et al. Eur Heart J Cardiovasc Imaging 2014;15:324-331

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2013. For permissions please email: journals.permissions@oup.com

Proposed algorithm to guide cardioprotective therapy based on sequential evaluation of LV strain.

Negishi K et al. Eur Heart J Cardiovasc Imaging 2014;15:324-331

Linear regression analysis between area strain and 2D LVEF and 3D LVEF and receiver-operating characteristic curves.

Altman M et al. Eur Heart J Cardiovasc Imaging 2014;15:316-323©

Linear regression and Bland–Altman analyses for global strain parameters between 2D and 3D modes.

Altman M et al. Eur Heart J Cardiovasc Imaging 2014;15:316-323©

Measurements of the left ventricular volumes, ejection fraction and deformation parameter area strain, using three-dimensional speckle-tracking echocardiography.

Altman M et al. Eur Heart J Cardiovasc Imaging 2014;15:316-323©

A systematic review of diastolic stress tests in heart failure with preserved ejection fraction, with proposals from the EU‐FP7 MEDIA study group

European Journal of Heart FailureVolume 16, Issue 12, pages 1345-1361, 12 NOV 2014 DOI: 10.1002/ejhf.184http://onlinelibrary.wiley.com/doi/10.1002/ejhf.184/full#ejhf184-fig-0001

A systematic review of diastolic stress tests in heart failure with preserved ejection fraction, with proposals from the EU‐FP7 MEDIA study group

European Journal of Heart FailureVolume 16, Issue 12, pages 1345-1361, 12 NOV 2014 DOI: 10.1002/ejhf.184http://onlinelibrary.wiley.com/doi/10.1002/ejhf.184/full#ejhf184-fig-0002

A systematic review of diastolic stress tests in heart failure with preserved ejection fraction, with proposals from the EU‐FP7 MEDIA study group

European Journal of Heart FailureVolume 16, Issue 12, pages 1345-1361, 12 NOV 2014 DOI: 10.1002/ejhf.184http://onlinelibrary.wiley.com/doi/10.1002/ejhf.184/full#ejhf184-fig-0003

Subgroup of pts with reduced systolic LVEF (≤50%) undergoing renal denervation (n = 19) and controls (n = 3) at baseline and at 6-month follow-up.

Felix Mahfoud et al. Eur Heart J 2014;35:2224-2231

LV mass index at baseline and 6-month follow-up in pts undergoing renal denervation (n = 55) and controls (n = 17)

Felix Mahfoud et al. Eur Heart J 2014;35:2224-2231

Subgroup of pts with reduced myocardial contractility (diastolic dysfunction, renal denervation: n = 27; control: n = 10) at baseline and 6-month follow-up evaluated by

measurements of circumferential strain.

Felix Mahfoud et al. Eur Heart J 2014;35:2224-2231

Use of cardiac imaging for the management of patients with chronic systolic heart failure.

Alessia Gimelli et al. Eur Heart J 2014;35:3417-3425

Example of cardiac magnetic resonance late gadolinium enhancement patterns in different aetiologies of heart failure.

Alessia Gimelli et al. Eur Heart J 2014;35:3417-3425

Accuracy for predicting recovery of regional dysfunction in heart failure patients.

Alessia Gimelli et al. Eur Heart J 2014;35:3417-3425

Late gadolinium enhancement SPECT