…..details about Molecule Profile

Presented By:-Manish Ranjan Singh

CisatracuriumGeneric Name:

Cisatracurium BesylateBrand Name/ Trade Name:

NimbexTherapeutic Classification : 

Neuromuscular Blocking Agent (NMB)

Storage Conditions : Store it in refrigerator (2° to 8°C)

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Physicochemical characteristicsSource:

     one of the 10 isomers of atracurium besylate

Molecular weight:     Cisatracurium: 929.2      Cisatracurium besylate: 1243.51

pH:     Cisatracurium injection: 3.25 to 3.65.

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Cisatracurium : AbstractsA non-depolarizing skeletal muscle relaxant Used as an adjunct to general anesthesiaIt is intermediate in its onset and duration

of actionProvides muscle relaxation during surgery,

medically assisted breathing, or insertion of a breathing tube

It is Neuromuscular Blocking Agent and belongs to benzylisoquinolinium class

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Cisatracurium is one of the ten isomers of the parent molecule, atracurium

Cisatracurium represents approximately 15% of the atracurium mixture

Cisatracurium is given as an injection through a needle placed into a vein or muscle i.e.- generally in hospital or surgical setting

Contraindicated to use in premature infants and patients with known hypersensitivity

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Dosing Forms And Strengths:Injectable Solution:

• 2 mg/ml• 10 mg/ml

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Possible side effects of Cisatracurium

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Neuromuscular Blocking AgentThis blocks neuromuscular transmission and

causes paralysis of the muscleNeuromuscular blocking agents are used as

an adjunct to anesthesiaNeuromuscular blocking agents are used in

the ICU setting for 3 reasons: i. to eliminate spontaneous breathing and

promote mechanical ventilationii. Cause a pharmacologic restraint so

patients do not harm themselvesiii. To decrease oxygen consumption

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