Cinderella is the first Dutch not-for-profit organization

making new drugs available for an

affordable price.

Cinderella focuses on step child drugs:Promising drugs, but of low interest to the commercial pharmaceutical industry due to their low potential to generate profits.

Cinderella is convincedthe clinical development of stepchild drugs can be completed successfully by the application on novel study methodology.

To reach this goalCinderella renounces the profit principle and adopts top clinical physician/scientists to execute her projects. Charity organizations and individuals who subscribe to Cinderella’s approach will provide the necessary financial support

.

Initiate development of stepchild drugs by initiating

clinical:

Renouncing the profit principle.

Selecting the most promising step child drugs.

Cinderella’s drug selection:

Drugs shelved by the pharmaceutical industry for their lack of profit

making potential.

Drugs promising

a high therapeutic ratio basedon results obtained in preclinical research and phase 1 studies.

Cinderella is only interested in phase 2 studies:

Phase 2 studies can be completed in a brief period of time at low costs

Short study duration

and low costs are achieved by entering limited numbers of patients

on study

(approx. 30).

Drugs shelved for their inability to generate a sizeable profit can still be

studied in patients.

Advantages of Cinderella’s approach:

Drugs shelved for their inability to generate a sizeable profit can still be

studied in patients.

All studies focused on improving the quality of lifeof the patient.

Top medical specialists are the

principal investigators.

Advantages of Cinderella’s approach:

Drugs shelved for their inability to generate a sizeable profit can still be

studied in patients.

All studies focused on improving the quality of lifeof the patient.

Top medical specialists are the

principal investigators.

Coordination is in the hands of the Cinderella Therapeutics Research Corporation.

Advantages of Cinderella’s approach:

Drugs shelved for their inability to generate a sizeable profit can still be

studied in patients.

All studies focused on improving the quality of life of the patient.

Top medical specialists are the

principal investigators.

Coordination is in the hands of the Cinderella Therapeutics Research Corporation.

A corporate approach leads to higher efficiency.

Advantages of Cinderella’s approach:

Advantages of Cinderella’s approach:

Cinderella subscribes to the open source principle.

Cinderella subscribes to the open source principle.

Obtained results will be published forthwith in scientific journals.

Advantages of Cinderella’s approach:

Cinderella subscribes to the open source principle.

Obtained results will be published forthwith in scientific journals.

Patent applications

to protect commercial

interests have become obsolete.

Advantages of Cinderella’s approach:

No

marketing costs.

Advantages of Cinderella’s approach:

No

marketing costs.

Therapies found to be ineffective in Cinderella studies will not

increase the price charged

for other, new and effective Cinderella therapies.

Advantages of Cinderella’s approach:

No

marketing costs.

Therapies found to be ineffective in Cinderella studies will not

increase the price charged

for other, new and effective Cinderella therapies.

Cinderella’s new type of drug development will be 10 to 100 times

cheaper than the current drug

development strategy of the Pharmaceutical Industry.

Advantages of Cinderella’s approach: