Post on 01-Mar-2021
Accepted Manuscript
Chiral pharmaceuticals: A review on their environmental occurrence and fateprocesses
Edmond Sanganyado, Zhijiang Lu, Qiuguo Fu, Daniel Schlenk, Jay Gan
PII: S0043-1354(17)30656-5
DOI: 10.1016/j.watres.2017.08.003
Reference: WR 13126
To appear in: Water Research
Received Date: 14 May 2017
Revised Date: 1 August 2017
Accepted Date: 2 August 2017
Please cite this article as: Sanganyado, E., Lu, Z., Fu, Q., Schlenk, D., Gan, J., Chiral pharmaceuticals:A review on their environmental occurrence and fate processes, Water Research (2017), doi: 10.1016/j.watres.2017.08.003.
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8 References 740
Aboul-Enein, H.Y., Ali, I., 2002. Chiral resolution of clenbuterol, cimaterol, and mabuterol on 741 Chirobiotic V, T, and TAG columns. J. Sep. Sci. 25, 851–855. 742
Agranat, I., Caner, H., Caldwell, J., 2002. Putting chirality to work: the strategy of chiral 743 switches. Nat. Rev. Drug Discov. 1, 753–68. 744
Ali, I., Saleem, K., Hussain, I., Gaitonde, V.D., Aboul Enein, H.Y., 2009a. Polysaccharides 745 chiral stationary phases in liquid chromatography. Sep. Purif. Rev. 38, 97–147. 746
Ali, I., Singh, P., Aboul-Enein, H.Y., Sharma, B., 2009b. Chiral analysis of ibuprofen residues in 747 water and sediment. Anal. Lett. 42, 1747–1760. 748
Allenmark, S., Gawronski, J., 2008. Determination of absolute configuration—An overview 749 related to this Special Issue. Chirality 20, 606–608. 750
Amorim, C.L., Moreira, I.S., Ribeiro, A.R., Santos, L.H.M.L.M., Delerue-Matos, C., Tiritan, 751 M.E., Castro, P.M.L., 2016. Treatment of a simulated wastewater amended with a chiral 752 pharmaceuticals mixture by an aerobic granular sludge sequencing batch reactor. Int. 753 Biodeterior. Biodegrad. 115, 277–285. doi:10.1016/j.ibiod.2016.09.009 754
Ardakani, Y.H., Mehvar, R., Foroumadi, A., Rouini, M.-R., 2008. Enantioselective 755 determination of tramadol and its main phase I metabolites in human plasma by high-756 performance liquid chromatography. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 757 864, 109–15. 758
Ariens, E.I., Wuis, E.W., Veringa, E.I., 1988. Stereoselectivity of bioactive xenobiotics: A pre-759 pasteur attitude in medicinal chemistry, pharmacokinetics and clinical pharmacology. 760 Biochem. Pharmacol. 37, 9–18. 761
Ariëns, E.J., 1986. Chirality in bioactive agents and its pitfalls. Trends Pharmacol. Sci. 7, 200–762 205. 763
Ariëns, E.J., 1984. Stereochemistry: A basis for sophisticated nonsense in pharmacokinetics and 764 clinical pharmacology. Eur. J. Clin. Pharmacol. 26, 663–668. 765
Arnold, K.E., Boxall, A.B.A., Brown, A.R., Cuthbert, R.J., Gaw, S., Thomas, H., Jobling, S., 766 Madden, J.C., Metcalfe, C.D., Naidoo, V., Shore, R.F., Smits, J.E., Taggart, M.A., 767 Thompson, H.M., 2013. Assessing the exposure risk and impacts of pharmaceuticals in the 768 environment on individuals and ecosystems Assessing the exposure risk and impacts of 769 pharmaceuticals in the environment on individuals and ecosystems. Biol. Lett. 9, 20130492. 770
Awad, H., El-aneed, A., 2013. Enantioselectivity of mass spectrometry: Challenges and 771 promises. Mass Spectrom. Rev. 32, 466–483. doi:10.1002/mas.21379 772
Bagnall, J., Malia, L., Lubben, A., Kasprzyk-Hordern, B., 2013. Stereoselective biodegradation 773
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