Post on 01-Apr-2015
Chapter 12, Drugs
Chapter 12, Drugs
Chapter 12, Drugs
Chapter 12, Drugs
Chapter 12, Drugs
Chapter 12, Drugs
Chapter 12, Drugs
Chapter 12, Drugs
Chapter 12 drugs, Penicillins
Chapter 12, drugs, Penicillium
Chapter 12, Drugs
Chapter 12, Drugs, Kirby-Bauer Test
Chapter 12, Drugs
Chapter 12, Drugs• Drug Resistance
– General cause: Genetic mutation, followed by • Natural selection
• 1. produce and enzyme (beta lactamase on penicillin
• 2. preventing penetration of drug• 3. pump drug out• 4. hereditary resistance due to transfer of
plasmids• 5. alteration of drugs active site
Chapter 12, Drugs• Contributors of overall drug resistance:
• 1. Indiscriminate use
• 2. Over use• 3. Underuse (take dosage as recommended)
• 4. Use of drugs in animal feed
Chapter 12, Drugs• Multiple Drug resistant strains
• 1. MRSA (HA and CA)
• 2. ViSA
• 3. MDR tb
• 4. MDR gononrrhea