Care of the Treatment-experienced Patient With HCV

Infection Who Failed Prior Therapy

Case53-year-old Black Man

Case (cont)

Case (cont)

Case (cont)

Second Treatment Regimen

Case (cont)

Why Is Achieving SVR So Important?

Why Is Achieving SVR So Important?

Potential Treatment Options for the Case Patient

Simeprevir for Treatment-naive Patients

Simeprevir for Treatment-experienced Patients

Sofosbuvir

COSMOSOff-Label Combination of Sofosbuvir and Simeprevir RBV in

Patients With G1 HCV Infection

SAPPHIRE-I and SAPPHIRE-II ABT-450/r (protease inhibitor and ritonavir) + ABT-

267 (NS5A inhibitor) + ABT-333 (non-nucleoside polymerase inhibitor) × 12 weeks

LONESTAR Trial Sofosbuvir and Ledipasvir Fixed-Dose

Combination RBV

Abbreviations

References

References (cont)