By Nick Murphy

Average age of patients is 51 years old Cancer of the cartilage cells in bones 40% of bone cancer cases Most common in arms, legs, or pelvis Men have same risk as women

Risk Factors: Multiple Exostoses

Cancer of bone matrix cells Males have greater risk than females Common in children/adolescents Even more common during “growth spurt”

Risk Factors: Inherited genetic disorders or syndromes Paget disease – severe

Tumor forms at base of skull/bones in spine Slow growth rate Likely to return if not removed completely Men have a greater risk than women

Risk Factors: Generally hereditary

Most common in children More common in Caucasian people Able to metastasize to lungs and other bones

Risk Factors: As mentioned, age, specifically young

Cancer of the bone marrow Able to metastasize

Occurs in older people Develops in soft tissue around bone Metastasizes to lungs and/or lymph nodes

Risk Factors: Generally hereditary Possibly high radiation exposure.

Surgery Wide excision Curettage Cryosurgery Bone cement

Radiation Therapy Very damaging

Chemotherapy Ewing’s & Osteosarcoma Metastasized

Target therapy Targets genes in cancer cells

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http://www.imageinterpretation.co.uk/images/tumour/Osteosarcoma.jpg http://radpod.org/wp-content/uploads/2007/06/chordoma.jpg http://imaging.birjournals.org/cgi/content/full/15/4/298/F4 http://upload.wikimedia.org/wikipedia/commons/2/21/Multiple_myeloma_(2)_HE_stain.jpg http://www.nature.com/modpathol/journal/v14/n10/images/3880420f3.jpg