Ancient Wisdom Modern Medicine

by Mark J Kaylor

Health Expenditures of Nations

2,000,000+ 284,000 3rd

13th

48th

40-60% $70,000

Mortality Rates

How do we best approach this?

Linear - One directionalTonic Systemic

Holistic

Mushrooms, not what you think

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Complexity of the Aging Process

“Winter worm, summer grass”

Dong chong xia cao

Cordyceps sinensis

The Tale of a “Yak-odisiac”

• Yak brought to higher grounds in the Spring would selectively graze in the new grass.

• Once the ate whatever it was they were looking for they became “friskier”.

• Turns out they were eating the Cordyceps.

• Word travelled to the Imperial Court

• Thus the fame of this “Yakodisiac” came to be.

Cordyceps Grown by Fermentation

• Yang Qi tonic• Anti-aging

• Enriches the Kidneys (Jing) & protects the Lungs

(Qi)• Dissolves phlegm • Heart and cardiovascular tonic• Enhance depressed immune function• Calm over active immune system • Sexual function restorative

Cordyceps’ Traditional Uses

Cordyceps - Rejuvenating Tonic

• Energy, Endurance,

Sports, Recovery

• Anti-oxidant

• Liver support,

esp.

hepatitis

• Anti-inflammatory

• Lowers cholesterol

• Respiratory support

• Restores adrenals

• Lowers blood pressure

• Increases SOD

• Prevents atherosclerosis

• Aides weight loss• Improved sleep quality• Increased oxygen uptake &

efficiency

• MAO inhibitor

Cordyceps’ – Traditional Kidney Tonic

Cordyceps’ – Traditional Heart Tonic

Cordyceps’ Traditional Longevity Tonic

Energy, Rejuvenation, & Vitality

Reishi-Ganoderma lucidum

Ling zhi (Spirit Plant)

Mushroom of Immortality

“…over a long period of time, agility of the body will

not cease, and the years are lengthened to those of the

Immortal Fairies.”

Reishi & TCM

• A traditional tonic to nourish, tonify and supplement the whole body

• Strengthens the lungs, protects and stimulates the liver and helps the body adapt to stress

• Removes toxins and disperses accumulation

Super tonic

“Tonic for the 21st century”

Reishi & Shen

Balance

Chaga - Inonotus obliquus

Chaga - Kabanoanatake

Wildcrafted Siberian Chaga

Chaga’s Diverse Benefits

Specific cancers tested with Chaga

• Human colon carcinoma

• Human gastric carcinoma

• Human breast adenocarcinoma

• Human hepato-cellular carcinoma

• Human HeLa cervical carcinoma

• Murine melanoma

• Human lung carcinoma

• Sarcomas

Chaga’s is Really All About

New to the West - Meshima

• Phellinus linteus

• Japanese call it “Meshimakobu”

• Grows on Mulberry, Elm and Willows

• Thousands of years of use in traditional medicine

• Nutrient-dense

Meshima’s Diverse Benefits

Immune Actions of Phellinus linteus

• Top immune enhancer out of ~20 medicinal mushrooms

• Study: 500 mg for 30 days

– Increased wbc ~11-81%

• Activates B cells

• Stimulates T lymphocytes

• Activates macrophage

• Orally effective

Meshima’s Effects on Breast cancer Growth

4,000,000,000,000

Brain Vulnerability

• Wear-and-tear

• Physical damage

• Sustained emotional stress

• Long term free radical damage

• Nutritional imbalances

• Lack of exercise

• Pesticides

• Pollution

• Herpes simplex virus 1

Alzheimer’s Disease Projections

Change in Number of Deaths2000 – 2008

Damage Caused by Amyloid Beta

Problem with Diagnosis & Treatment

1) Currently all medicine can do is maybe slow

progression

2) AD develops over a long time period with no signs or

symptoms

3) With too late of a diagnosis, neurons may be dead and

circuits may be destroyed

4) Almost impossible at this point to restore

5) PREVENT PREVENT PREVENT

What is alzheimer’s disease?

– memory loss

– language deterioration

– impaired ability to manipulate visual information

– poor judgment

– confusion

– restlessness

– mood swings

Eventually leads to loss of cognition, personality and function

So what kind of a disease is alzheimer’s?

Brain

Central Nervous System

What about? Inflammatory Immune Cardiovascular Free Radical Endocrine

Encarta World English Dictionary:

“senile dementia - a form of brain

disorder marked by progressive

and irreversible mental

deterioration, memory loss and

disorientation…”

Is there hope?

Lion’s Mane

Yamabushitake, Hou tou gu (Monkey’s Head), Bear’s Head, pom pom

NGF and the Brain

Lion’s Mane’s Actions

• Anti-tumor

• Immuno-modulating

• Cell growth regulating

• Macrophage activating

• Lymphocyte activating

• Anti-proliferative

• Anti-microbial

• Toxic to cancer cells

• Inhibiting cancer dna/rna

• Improves sleep apnea

• hiv-1 reverse transcriptase activity

• Cholesterol lowering

• Blood thinning

• Anti-oxidant

• Blood sugar lowering

• Anti-ulcer

• Benefits atrophic gastritis

• Anti-MRSA

• Reduces depression & anxiety

Amyloban 3399™

Contains Standardized Extracts of:

• Hericenones

► Stimulate production of Nerve Growth Factor

• Amyloban

► May prevent death of nerve cells caused by amyloid

beta peptides.

► Patented (Japanese Patent # 3943399)

Lion’s Mane Nerve Support

• Induction of NGF

• Inhibition of the cytotoxicity of β-amyloid peptide

• Protection against neuronal cell death

• Stimulates myelination

• Anti-oxidant properties

• Hypoglycemic effects

• Immune enhancement

Effects of Lion’s Mane on Nerve Cell Protection

• Looked at ER stress

induced neuronal cell

death

• Effectively protected cells

from death

Note: the crude extract,

Amyloban, appeared more

effective than purified DLPE

Lion’s Mane Clinical Study

• Rehabilitative hospital, Japan; elderly with degenerative diseases

• 6 of 7 dementia Patients improved perceptual capacities

• Marked improvements in patients evaluated by Functional

Independence Measure

• Appears to cross blood brain barrier

• Two other studies-retarded progression improved cognition

Double-blind Placebo-Controlled Yamabushitake Study

Lion’s Mane for Cognitive Impairment

• 18 patients with mild to moderate impairment• 1.5 grams of Lion’s Mane, 2x a day• Results:

– 9 of 18 saw improvement– 7 of 18 saw no change *– 2 of 18 got worse

Case Report on Amyloban

Before

• Anxious, hostile, impatient

• 29 dementia score

• 4 years ago, couldn’t name 4 vegetables

• Couldn’t cook

• “Scary” dreams

• Restless & uneasy

• Couldn’t do simple math

Case Report on Amyloban

After

• Even temperament

• Normal score

• Can name as many as you want

• Cooking

• Dreams of teaching dance

• Calm & comfortable

• Now she can

“The Little Root That Could”

Turmeric Benefits

Abscess, Adenoma, Adenosis, Allergy, Alzheimer’s, Amenorrhea, Anorexia, Arthrosis, Asthma,

Atherosclerosis, Athlete’s foot, Bacillus, Bacteria, Bite, Bleeding, Boil, Bowen’s disease, Bronchosis,

Bruise, Bursitis, Cancer, Cancer – abdomen, Cancer – bladder, Cancer – breast, Cancer cervix,

Cancer– colon, Cancer – duodenum, Cancer – esophagus, Cancer – joint, Cancer – liver, Cancer –

mouth, Cancer – skin, Cancer – stomach, Cancer – uterus, Cardiopathy, Cataract, Catarrh, Chest

ache, Childbirth, Cholecystosis, Circulosis, Cold, Colic, Coma, Congestion, Conjuctivosis,

Constipation, Coryza, Cramp, Cystosis, Dermatosis, Diabetes, Diarrhea, Dropsy, Duodenosis,

Dysgeusia, Dysmenorrhea, Dyspepsia, Dysuria, Eczemia, Edema, Elephantiasis, Enterosis, Epilepsy,

Epistaxis, Esophagosis, Fever, Fibrosis, Fungus, Gallstone, Gastrosis, Gonorrhea, Gray hair,

Headache, Hematemesis, Hematuria, Hemorroid, Hepatosis, High blood pressure, High cholesterol,

High triglycerides, Hyper- lipidemia, Hysteria, Immunodepression, Infection, Inflammation, Itch,

Jaundice, Laryngosis, Leprosy, Leukemia, Leishmania, Leukoderma, Leukoplakia, Lymphoma,

Malaria, Mania, Morning sickness, Mucososis, Mycosis, Nematode, Nephrosis, Nervousness,

Ophthalmia, Osteoarthrosis, Ozena, Pain, Parasite, Polyp, Psoriasis, Puerperium, Radiation injury,

Restenosis, Rheumatism, Rhinosis, Ring worm, Scabies, Small pox, Sore, Sore throat, Sprain, Stone,

Staphylococcus, Stroke, Swelling, Syphilis, Trauma, Ulcer, Uveosis, Vertigo, Vomiting, Wart, Water

retention, Whitelow, Worm, Wound, Yeast (Duke 2003).

Berries, A True Superfood

• Anti-inflammatory• Anti-oxidant, esp.

cardiovascular • Immune functions• Urinary tract health

• Improves memory

• Prevents brain oxidation

• Supports a healthy brain

• Anti-bacterial

• Decrease cancer risk

• Anti-mutagenic

• Increase tumor suppressor

genes

• Inhibit metastasis

• Lowers LDL

• Vision health

• Oral health

Schizandra - Wu Wei Zi

• Supports all 3 Treasures• Builds primary life-energy• Rejuvenates Qi & Jing• Supports & protects liver• Improves vision• Youth preserving• Purifies the blood• Adaptogen & antioxidant

Schizandra, Traditional Tonic

Use for 100 days in a row:

• purify blood

• sharpen mind

• improve memory

• rejuvenate Qi

• cause skin to become radiantly

beautiful

The Story of Yang Guifei

One of China 4 most beautiful women

Said to be so beautiful that flowers would bow before her beauty

One of her beauty secrets: Tremella

Tremella is a traditinal Yin tonic

Maitake’s (Holistic) Immune Benefits

Direct

• Prevent mutation• Immune stimulation• Increase phagocytosis• Activate NK cells• Improved functionality• Apoptosis• Potentiate therapy• Recovery• Targeting• Metastasis inhibition

Supportive

• Anti-oxidant• Anti-inflammatory• Lowers blood sugar• Lowers insulin levels• Liver protecting• Liver detoxifying• Endocrine balancing• Inhibit platelet

aggregation

Chinese or Korean Ginseng

Panax = panacea

Tonic Uses of Ginseng

• Strengthen the whole body

• Improve overall functioning

• Normalizing action on the body

• Restorative & rejuvenating

• “Tonic” to central nervous system, digestive &

respiratory tract

• Ultimate adaptogen

•Builds and supports all 3 Treasures

Qi, Shen and Jing

• “Closest thing to a panacea that we have”

He shou wu

• Li Ching Yuen 256 yrs. Old

• Yin Jing tonic

• Increases SOD activity

• 50 yr old - grey hair black

• 100 yr old - youthfulness

• 300 yr old - immortality

He Shou Wu

• Traditional “youthfulness” tonic (Yin Jing)

• Supplements Qi & Blood

• Invigorates Liver & Kidneys

• Anti-bacterial, antioxidant, anti-inflammatory

• Strengthen lower back, knees & connective tissues

• Strengthens & supports red blood cells

The New Pharmacology: “Farmacolgy”

Thank you

Questions ?

Comments ?

Feedback ?

mjk@mushroomwisdom.com

Pre-Clinical Studies

3 studies tested Lion’s Mane:

① 7 patients with dementia were given LM powder, showed improvement in daily living activity

② 15 patients with dementia showed similar improvement with LM tablets.

③ 7 patients with Alzheimer’s showed improvement in their peripheral symptoms with LM tablets (wandering, aggressiveness).

Effects of Cs-4 on Senescence