1970s 1975 1980 1985 1990 1992 1994 1995 1996 1997 1998 1999 2000 2001 2002 2004 2006

FunctionalGenetics

From …FunctionalGenomics

… to …

Evolution of biomedical innovation potential …

An Integrative Approach for Discovery of Gene Functionin Immunological Disease

New Animal Models

Functional Genetics

Molecular & Cellular pathways

SensitizedENU mutagenesis

Expression profiling

Cross platform validation(GO, QTLs, human)

Gene & pathwayprediction

Gene & pathway validation in animal models

New knowledge & Innovation

€ € € €

ResearchBusiness

The Greek perspective;

Can we succeed in a new knowledge-driven economy?

• Excellent Greek scientists exist all over the world (including Greece)

• EU membership

• Small country providing advantages on focus and synergies

• Biomedical Research highly fragmentedBiomedical Research highly fragmented

• National Policies and Instruments still pendingNational Policies and Instruments still pending

• Industrial collaborations without impactIndustrial collaborations without impact

• Nuclei of excellence still existNuclei of excellence still exist

• Reforms and investment necessaryReforms and investment necessary

… … on researchon research

A few Recommendations for an Integrated Support of the Greek Research Environment

• Integrated design based on excellence and first-rate scientists

• Meritocracy and accountability – follow international standards

• Foster creative research careers of outstanding young researchers

• Develop large infrastructures / projects needed for innovation

• Incubate technology transfer structures with free academic research

• Invest more on Research Institutes (rather than Universities)

• Reform National Research Funding System (involve stakeholders)

• Lack of entepreneurship and business skillsLack of entepreneurship and business skills

• Little help for start-ups Little help for start-ups (IPR management, financing, management)(IPR management, financing, management)

• Limited access to knowledge portfolios Limited access to knowledge portfolios

• Need for a common vision between R&BNeed for a common vision between R&B

• Reforms and investment necessaryReforms and investment necessary

… … on commercializationon commercialization

A few Recommendations for an Integrated Support of the Greek Innovative Business Environment

• High standards incubating facilities / clusters

• IPR assistance and management for Biotech

• Financing and further organizational support

• Support for further R&D in start-ups

• Integrated National Innovation System

• Business start-up incentives and assistance or mentoring

BIOMEDICAL SCIENCES RESEARCH CENTREBIOMEDICAL SCIENCES RESEARCH CENTRE ‘‘ALEXANDER FLEMINGALEXANDER FLEMING’’

A European Centre of Excellence in Functional GenomicsA European Centre of Excellence in Functional Genomics

Mouse ClinicTechnologyIncubator

ResearchInstitutes

((Vari – Greece)Vari – Greece)