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S23Poster Abstracts / 48 (2011) S18–S120

10.

ORTHOSTATIC TOLERANCE TESTING IN A PROSPECTIVECOHORT OF ADOLESCENTS WITH CHRONIC FATIGUESYNDROME AND RECOVERED CONTROLS FOLLOWINGINFECTIOUS MONONUCLEOSISBen Katz1, Julian Stewart, MD, PhD3, Yukikohiraishi, PhD4, Cynthia Mears, AssociateProfessor1, Cynthia Mears, DO2, Renee Taylor,A, PhD5. 1Feinberg School of Medicine andhildren’s Memorial Hospital 2Feinberg School

of Medicine, Northwestern University andChildren’s Memorial Hospital 3New YorkMedical College 4Private Practice 5University ofllinois at Chicago

Purpose: Tomeasure standing orthostatic tolerance in adoles-cents with CFS and controls 6 months following IMMethods: Thirty-six adolescents diagnosedwith CFS 6monthsfollowing IM and 45 recovered controls completed question-naires regarding autonomic symptoms and had standing or-thostatic tolerance testing (SOTT) performed. The �2 analysisand Spearman correlations were used to correlate the resultsof SOTT and the diagnosis of CFS. Pearson and Spearman cor-relations were performed to study the relationships betweenSOTT, the diagnosis of CFS, and the number of autonomicsymptoms present.Results: Adolescents diagnosed with CFS and recovered con-trols did not differ significantly in age, weight, or body-massindex. Therewas a correlation between autonomic symptoms,standing orthostatic intolerance and the diagnosis of CFS at 6months. There was also a correlation between autonomicsymptoms at baseline and the diagnosis of CFS at 6 months.Conclusions: Adolescents who meet the criteria for CFS 6months following IM have, as a group, more standing ortho-static intolerance, and autonomic symptoms than recoveredcontrols. Thosewhoweremore tired at baseline also hadmoreautonomic symptoms 6 months following mononucleosis.Whether these abnormal findings are a cause or effect of CFS orwhether they can be used to determine objectively whichadolescents following IM will develop CFS remains to be de-termined. However, this study uniquely and prospectivelydemonstrates that IM produces both fatigue and associatedorthostatic intolerance in a subset of patients.Sources of Support: R01HD4330101A1 from the National In-stitute of Child Health and Human Development.

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COMMUNITY BASED SCREENING AND MANAGEMENT OFADOLESCENT ANEMIA IN TRIBAL AREAS OF INDIA KEY TOREDUCTION IN MATERNAL MORTALITYArchana Joshi, Post Graduation in Foods andNutrition. Deepak Foundation

Purpose: Prevention of anemia amongst adolescent girls has areat potential in reducing the risk of maternal death. Morehan half of young adolescents in Gujarat State of India, arenemic and its prevalence is considerably higher among thosen (74%). While many school and clinic based interventions

ave shown promising results, albeit with poor scalability and

eplicability, community based interventionswithin the exist-ng government delivery system are scarce.ethods: Deepak Foundation, a voluntary agency initiatedcreening of young mothers for anemia to promote compli-nce for consumption of iron and folic acid (IFA) supplementnd referral of severely anemic mothers at tertiary care facili-ies. The Foundation is implementing anemia control programACP) as part of a larger intervention Safe Motherhood andhild Survival project covering 700,000 tribal populations inhe district in partnership with the Government of Gujarat.he ACP leverages on monthly nutrition and health daysNHD) campaigns held in all village jointly by the Departmentf Health and Family Welfare andWomen and Child Develop-ent to provide preventive, promotive, and curative healthnd nutrition services towomen and children. The joint initia-ive is conducted with active involvement of village basedommittees Apart from conducting blood and urine test, infor-ation on prevention and control of anemia by demonstrationf recipes made locally available, culturally acceptable, ironich ingredients, distribution of IFA and deworming tablets,nd identification of severely anemic girls, their counselingnd referral to equipped health centers are also facilitatedhrough the campaign based approach of the intervention.ach beneficiary is provided with a color-coded card specify-ng the blood group, Hb and glucose level to motivate him orer to comply with appropriate treatment.esults: A total of 322 campaigns were conducted during aeriod of 7 months (i.e., January-July 2010) in which 1810 ado-escent girls were covered. Screening for anemia showed thatearly 95.3% of these girls were anemic (Hb �12 g/dL), 53.6 %eremoderately anemic (Hb7-9.9 g/dL) and2.2 %were severelynemic (Hb�7g/dL). IFA tablets through theGovernment’s stockere distributed to 81.7% girls anddeworming to 4% girls. A totalf 42.5% of severely anemic girls were able to access appropriatereatment (double IFA supplements, blood transfusion, intra-ve-ous injectable iron) at equipped health facilities. As early mar-iage (before 18 years) is common in these areas, asmany as 9.6%f these adolescent girls were pregnant and 12.3%were nursing,ndicating much higher iron requirements over and above thatequired for their own growth.onclusions: The prevalence of anemia was disproportionatelyigh among tribal women due to poverty, inadequate diet, prev-lenceof sickle cell anemia, tapeworminfestation,malaria, phys-ological conditions pregnancy and lactation, and poor access toealth services. Factors such as timely screening of youngomen for anemia, compliance to intake of iron supplementsnd the correct estimates on prevalence of the problem are im-erative to design appropriate and intensive intervention strat-gy for curtailing anemia among young women who die need-essly during pregnancy and postpartum period in tribal areas.ources of Support: Deepak Group of Companies (website:ww.deepakfoundation.org).

12.

SOURCES OF FOLATE, VITAMIN D, AND CALCIUM IN URBANADOLESCENT FEMALESEvan Howe, PhD, MPH1, Andrea Bonny, MD2.1Case Western Reserve University 2MetroHealthedical Center